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Measuring the composition-curvature coupling in binary lipid membranes by computer simulations
(American Institute of Physics, 2014-11)
The coupling between local composition fluctuations in binary lipid membranes and curvatureaffects the lateral membrane structure. We propose an efficient method to compute the composition-curvature coupling in molecular ...
Effect of N-terminal acetylation on lytic activity and lipid-packing perturbation induced in model membranes by a mastoparan-like peptide
(Elsevier Science, 2018-03)
L1A (IDGLKAIWKKVADLLKNT-NH2) is a peptide that displays a selective antibacterial activity to Gram-negative bacteria without being hemolytic. Its lytic activity in anionic lipid vesicles was strongly enhanced when its ...
Effects of phenylalanine on the liquid-expanded and liquid-condensed states of phosphatidylcholine monolayers
(SAGE Publications, 2019-01)
Background: Phenylalanine (Phe) is involved in physiological and pathological processes in cell membranes in which expanded and condensed states coexist. In this direction, it was reported that surface hydration is important ...
Molecular-Level Modifications Induced by Photo-Oxidation of Lipid Monolayers Interacting with Erythrosin
(2016-05-03)
Incorporation into cell membranes is key for the action of photosensitizers in photomedicine treatments, with hydroperoxidation as the prominent pathway of lipid oxidation. In this paper, we use Langmuir monolayers of ...
Lipid model membranes for drug interaction study
(SpringerNew YorkEUA, 2006)
Effect of N-terminal acetylation on lytic activity and lipid-packing perturbation induced in model membranes by a mastoparan-like peptide
(2018-03-01)
L1A (IDGLKAIWKKVADLLKNT-NH2) is a peptide that displays a selective antibacterial activity to Gram-negative bacteria without being hemolytic. Its lytic activity in anionic lipid vesicles was strongly enhanced when its ...
Inter-domain interactions in charged lipid monolayers
(American Chemical Society, 2014-01)
Phase coexistence is common in model biomembranes with the presence of domains formed by lipids in a dense phase state modulating lateral diffusion of species through hydrodynamic and electrostatic interactions. In this ...
Molecular-level insight into the binding of arginine to a zwitterionic Langmuir monolayer
(Royal Society of Chemistry, 2017-06)
Solutions of the cationic amino-acid arginine (Arg+) in contact with a phospholipid monolayer are investigated by molecular dynamics simulations. The results show that Arg+ binds strongly to the lipid/water interface, with ...
Rat osseous plate alkaline phosphatase as Langmuir monolayer - An infrared study at the air-water interface
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
A glycosylphosphatidylinositol (GPI)-anchored enzyme (rat osseous plate alkaline phosphatase-OAP) was studied as monolayer (pure and mixed with lipids) at the air-water interface. Surface pressure and surface potential-area ...
Interaction between 17 α-ethynylestradiol hormone with Langmuir monolayers: The role of charged headgroups
(2017-10-01)
The persistence of steroid hormones disposed of in the environment may pose risks to the health of humans and wildlife, which brings the need of understanding their mode of action, believed to occur in cell membranes. In ...