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Alterations in myocardial collagen content affect rat papillary muscle function
(Amer Physiological Soc, 2000-10-01)
We investigated the influence of myocardial collagen volume fraction (CVF, %) and hydroxyproline concentration (mu g/mg) on rat papillary muscle function. Collagen excess was obtained in 10 rats with unilateral renal ...
Alterations in myocardial collagen content affect rat papillary muscle function
(2000-01-01)
We investigated the influence of myocardial collagen volume fraction (CVF, %) and hydroxyproline concentration (μg/mg) on rat papillary muscle function. Collagen excess was obtained in 10 rats with unilateral renal ischemia ...
Pro-fibrotic effect of oxidized LDL in cardiac myofibroblasts
(Elsevier, 2020)
Inflammatory signals associated with cardiac diseases trigger trans-differentiation of cardiac fibroblasts to cardiac myofibroblasts. Cardiac myofibroblasts are the main cell type involved in the development of cardiac ...
Effects of early aldosterone antagonism on cardiac remodeling in rats with aortic stenosis-induced pressure overload
(2016-11-01)
Aldosterone plays a pivotal role in the pathophysiology of systolic heart failure. However, whether early aldosterone antagonism improves cardiac remodeling during persistent pressure overload is unsettled. We evaluated ...
The effect of non-antihypertensive doses of angiotensin converting enzyme inhibitor on myocardial necrosis and hypertrophy in young rats with renovascular hypertension
(1999-05-06)
In renovascular hypertensive rats, low doses of angiotensin converting enzyme (ACE) inhibitors have been found to prevent myocardial hypertrophy independent of blood pressure level. This finding would suggest humoral rather ...
The effect of non-antihypertensive doses of angiotensin converting enzyme inhibitor on myocardial necrosis and hypertrophy in young rats with renovascular hypertension
(1999-05-06)
In renovascular hypertensive rats, low doses of angiotensin converting enzyme (ACE) inhibitors have been found to prevent myocardial hypertrophy independent of blood pressure level. This finding would suggest humoral rather ...
Anatomical and pathological findings in hearts from fetuses and infants with cardiac manifestations of neonatal lupus
(OXFORD UNIV PRESS, 2012)
Objective. The autopsy and clinical information on children dying with anti-SSA/Ro-associated cardiac manifestations of neonatal lupus (cardiac NL) were examined to identify patterns of disease, gain insight into pathogenesis ...
Growth hormone attenuates skeletal muscle changes in experimental chronic heart failure
(Churchill Livingstone, 2014)