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Auditoría de medicación antiangiogénica utilizada en oftalmología vía intravítrea
(2022-06-07)
Este estudio se propuso evaluar el nivel de conocimiento de médicos auditores en patologías oftalmológicas donde se utiliza medicación antiangiogénica intravítrea, además, identificar los beneficios de estas drogas y la ...
Preclinical efficacy of [V 4 Q 5 ]dDAVP, a second generation vasopressin analog, on metastatic spread and tumor-associated angiogenesis in colorectal cancer
(Korean Cancer Association, 2018-06)
Purpose Control of metastatic spread of colorectal cancer (CRC) remains as a major therapeutic challenge. [V 4 Q 5 ]dDAVP is a vasopressin peptide analog with previously reported anticancer activity against carcinoma tumors. ...
Antiangiogenic activity and direct antitumor effect from a sulfated polysaccharide isolated from seaweed
(Elsevier B.V., 2013-07-01)
Angiogenesis is a dynamic proliferation and differentiation process. It requires endothelial proliferation, migration and tube formation. in this context, endothelial cells are a preferred target for several studies and ...
Eficácia e segurança dos antiangiogênicos no tratamento da retinopatia da prematuridade : revisão sistemática e metanálise
(Universidade Estadual Paulista (Unesp), 2018-07-25)
Background: The standard treatment of retinopathy of prematurity (ROP) is the ablation of the avascular retina with laser or cryotherapy. However, this therapy may leave permanent structural and visual sequelae and may not ...
Evaluation of antitumor activity of long-circulating and ph-sensitive liposomes containing ursolic acid in animal models of breast tumor and gliosarcoma.
(Universidade Federal de Minas GeraisBrasilFAR - DEPARTAMENTO DE PRODUTOS FARMACÊUTICOSICB - DEPARTAMENTO DE PATOLOGIAUFMG, 2016)
Fact or Fiction, It Is Time for a Verdict on Vasculogenic Mimicry?
(Facultad de Medicina y CienciaCentro de Biología Celular y Biomedicina CEBICEM, 2019)
The term vasculogenic mimicry (VM) refers to the capacity of certain cancer cells to form fluid-conducting structures within a tumor in an endothelial cell (EC)-free manner. Ever since its first report by Maniotis in 1999, ...
Thrombospondin-1 (TSP-1) Analogs ABT-510 and ABT- 898 Inhibit Prolactinoma Growth and Recover Active Pituitary Transforming Growth Factor-b1 (TGF-b1)
(Endocrine Society, 2012-06-14)
Prolactinomas are the most prevalent type of secreting pituitary tumors in humans and generally respond well to a medical therapy with dopamine agonists. However, for patients exhibiting resistance to dopaminergic drugs, ...
Role of androgen and vitamin D receptors in endothelial cells from benign and malignant human prostate
(AMER PHYSIOLOGICAL SOC, 2013)
Forty years ago, Judah Folkman (Folkman. N Engl J Med 285: 1182-1186, 1971) proposed that tumor growth might be controlled by limiting formation of new blood vessels (angiogenesis) needed to supply a growing tumor with ...