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Role of hippocampal signaling pathways in long-term memory formation of a nonassociative learning task in the rat
(Cold Spring Harbor Lab Press, 2000-09)
Long-term habituation to a novel environment is one of the most elementary forms of nonassociative learning. Here we studied the effect of pre- or posttraining intrahippocampal administration of drugs acting on specific ...
p38 mitogen activated protein kinase mediates cardiac Na+/H+ exchanger inhibition induced by Sildenafil
(Elsevier Science, 2019-04-15)
Since the original description as potent antianginal compounds, phosphodiesterase 5A inhibitors have continuously increased their possible therapeutic applications. In the heart, Sildenafil was shown to protect against an ...
Reconsolidação da memória de extinção: análise farmacológica, bioquímica e molecular
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2015)
Background : Therapies based on the impairment of memory reconsolidation or the enhancement of extinction learning offer the possibility of diminishing the impact caused by the persistent recollection of traumatic events. ...
Análise neurofarmacológica e neuroquímica da expressão de memórias espaciais
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2012)
Memories are not stored in its final form immediately after the acquisition. They undergo a long stabilization process known as consolidation. Consolidated memories can become labile again after the retrieval and susceptible ...
CLASSICAL AVERSIVE CONDITIONING INDUCES INCREASED EXPRESSION OF MATURE-BDNF IN THE HIPPOCAMPUS AND AMYGDALA OF PIGEONS
(Pergamon-elsevier Science LtdOxfordInglaterra, 2013)