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Amyloid formation by short peptides in the presence of dipalmitoylphosphatidylcholine membranes
(American Chemical Society, 2020-11-19)
The aggregation of two short peptides [RF] and [RF]4 (where R = arginine and F = phenylalanine) with dipalmitoylphosphatidylcholine (DPPC) model membranes was investigated at the air-water interface using the Langmuir ...
Aggregation limiting cell-penetrating peptides derived from protein signal sequences
(MDPI, 2023-02-16)
Alzheimer’s disease (AD) is the most common neurodegenerative disease (ND) and the leading cause of dementia. It is characterized by non-linear, genetic-driven pathophysiological dynamics with high heterogeneity in the ...
DETERMINACIÓN DE LAS CONCENTRACIONES DE AMILOIDE β40 Y AMILOIDE β42 EN EL LÍQUIDO AMINIÓTICO DE MUJERES EMBARAZADAS CON FETOS CON TRISOMIA 21
(Facultad de Medicina de la Universidad Central de Venezuela., 2022)
Chemical characterization of pro-inflammatory amyloid-beta peptides in human atherosclerotic lesions and platelets
(Elsevier Science, 2011)
Amyloid-β (Aβ) peptides are intimately involved in the inflammatory pathology of atherosclerotic vascular disease (AVD) and Alzheimer's disease (AD). Although substantial amounts of these peptides are produced in the ...
Amyloid-β peptide remnants in AN-1792-immunized Alzheimer's disease patients: A biochemical analysis
(Amer Soc Investigative Pathology, Inc, 2006-12)
Experiments with amyloid-β (Aβ)-42-immunized transgenic mouse models of Alzheimer's disease have revealed amyloid plaque disruption and apparent cognitive function recovery. Neuropathological examination of patients ...
Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice
(Portland Press Ltd., 2017)
Cerebral hypoperfusion is an early feature of Alzheimer's disease (AD) that influences the progression from mild cognitive impairment to dementia. Understanding the mechanism is of critical importance in the search for new ...
Effect of trehalose on the interaction of Alzheimer's Aβ-peptide and anionic lipid monolayers
(Elsevier Science, 2011-01)
The interaction of amyloid β-peptide (Aβ) with cell membranes is believed to play a central role in the pathogenesis of Alzheimer's disease. In particular, recent experimental evidence indicates that bilayer and monolayer ...
Release of Acetylcholinesterase (AChE) from β-Amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice
(2008)
The major protein constituent of amyloid deposits in Alzheimer's disease (AD) is the amyloid-beta-peptide (Abeta). Amyloid deposits contain "chaperone molecules" which play critical roles in amyloid formation and toxicity. ...
Release of Acetylcholinesterase (AChE) from β-Amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice
(2008)
The major protein constituent of amyloid deposits in Alzheimer's disease (AD) is the amyloid-beta-peptide (Abeta). Amyloid deposits contain "chaperone molecules" which play critical roles in amyloid formation and toxicity. ...