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Periapical lesions decrease insulin signal and cause insulin resistance
(2013-05-01)
Introduction: Inflammatory cytokines are associated with decreased insulin signal transduction. Moreover, local oral inflammation, such as that accompanying periodontal disease, is associated with insulin resistance and ...
TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient - Effects on leptin and insulin signaling pathways
(Elsevier B.V., 2007-05-01)
Acting in the hypothalamus, tumor necrosis factor-alpha (TNF-alpha) produces a potent anorexigenic effect. However, the molecular mechanisms involved in this phenomenon are poorly characterized. In this study, we investigate ...
Insulin and Leptin Signaling in Placenta from Gestational Diabetic Subjects
(Georg Thieme Verlag Kg, 2015-11)
Insulin and leptin receptors are known to share signaling pathways, such as JAK2/STAT-3 (Janus kinase2/signal transduction and activator of transcription3), MAPK (Mitogen activated protein kinase), and PI3K (phosphoinositide ...
Acute exercise decreases PTP-1B protein level and improves insulin signaling in the liver of old rats
(2013-02-25)
It is now commonly accepted that chronic inflammation associated with obesity during aging induces insulin resistance in the liver. In the present study, we investigated whether the improvement in insulin sensitivity and ...
Acute exercise decreases PTP-1B protein level and improves insulin signaling in the liver of old rats
(2013-02-25)
It is now commonly accepted that chronic inflammation associated with obesity during aging induces insulin resistance in the liver. In the present study, we investigated whether the improvement in insulin sensitivity and ...