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Hypotensive and vasorelaxing effects of the new NO-donor [Ru(terpy)(bdq)NO+](3+) in spontaneously hypertensive rats
(Academic Press Inc. Elsevier B.V., 2012-02-15)
Drugs that release nitric oxide (NO) usually have limitations due to their harmful effects. Sodium nitroprusside (SNP) induces a rapid hypotension that leads to reflex tachycardia, which could be an undesirable effect in ...
The novel serine protease PreR-Co promotes endothelium-independent vasorelaxation in rabbit aortic rings
(American Physiological Society, 2003-02)
The effect of a novel enzyme (PreR-Co) that activates renal prorenin was studied on rabbit aortas with and without endothelium. It was tested 1) in the basal tone of nonstimulated or ANG II-sensitized rings or rings ...
Obtenção e avaliação farmacológica de complexos de inclusão (geraniol em beta-ciclodextrina) sobre o sistema cardiovascular de ratos
(Universidade Federal de SergipePós-Graduação em BiotecnologiaBrasilUFS, 2017)
Endothelium-Dependent Vasorelaxant Effect of Butanolic Fraction from Caryocar brasiliense Camb. Leaves in Rat Thoracic Aorta
(HINDAWI PUBLISHING CORPORATIONNEW YORK, 2012)
Caryocar brasiliense Camb. "pequi" is a native plant from the Cerrado region of Brazil that contains bioactive components reported to be antioxidant agents. Previous work has demonstrated that dietary supplementation with ...
Compound 48/80 induces endothelium-dependent and histamine release-independent relaxation in rabbit aorta
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
Compound 48/80 (C48/80) is a synthetic condensation product of N-methyl-p-methoxyphenethyl am me with formaldehyde and is an experimental drug used since the 1950s to induce anaphylactic shock through histamine release. ...
Discovery of new phthalazinones as vasodilator agents and novel pharmacological tools to study calcium channels
(Future Medicine Ltd., 2019)
Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta
(2016)
The vascular endotheliumplays an essential role in the control of the blood flow. Pharmacological agents like quinone (menadione) at various doses modulate this process in a variety of ways. In this study, Q7, a ...
Evaluación vascular y efecto hipotensor de plantas del género marila
(2008-03-01)
El objetivo de este estudio fue determinar el perfil de actividad cardiovascular de diferentes extractos de las plantas Marila laxiflora y Marila pluricostata pertenecientes al género Marila. En estudios in vitro realizados ...
Evaluación vascular y efecto hipotensor de plantas del género marila
(2008-03-01)
El objetivo de este estudio fue determinar el perfil de actividad cardiovascular de diferentes extractos de las plantas Marila laxiflora y Marila pluricostata pertenecientes al género Marila. En estudios in vitro realizados ...