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Phosphatidic acid induces ligand-independent epidermal growth factor receptor endocytic traffic through pde4 activation
(AMER SOC CELL BIOLOGY, 2010)
Mechanotransduction pathways in skeletal muscle hypertrophy
(INFORMA HEALTHCARELONDON, 2012)
In the last decade, molecular biology has contributed to define some of the cellular events that trigger skeletal muscle hypertrophy. Recent evidence shows that insulin like growth factor 1/phosphatidyl inositol 3-kinase/protein ...
Galectin-8 Induces Apoptosis in Jurkat T Cells by Phosphatidic Acid-mediated ERK1/2 Activation Supported by Protein Kinase A Down-regulation
(2009)
Galectins have been implicated in T cell homeostasis playing complementary pro-apoptotic roles. Here we show that galectin-8 (Gal-8) is a potent pro-apoptotic agent in Jurkat T cells inducing a complex phospholipase ...
Phospholipases in Nitric Oxide-Mediated Plant Signalling
(Springer, 2014)
Nitric Oxide (NO) is an important redox-based regulator of cell physiology involved in many signaling processes in plants. The precise molecular mechanism of how NO interacts with or activates different targets is still ...
Plasma Membrane Calcium Pump (PMCA) differential exposure of hydrophobic domains after calmodulin and phosphatidic acid activation
(American Society for Biochemistry and Molecular Biology, 2011-05)
The exposure of the plasma membrane calcium pump (PMCA) to the surrounding phospholipids was assessed by measuring the incorporation of the photoactivatable phosphatidylcholine analog [125I]TID-PC/16 to the protein. In the ...
A kinetic study of phospholipids extraction by degumming process in sunflower seed oil
(Springer, 2000-12)
During the refining process of vegetable oils (degumming), phospholipids are eliminated by thermal treatment with water (hydratable phospholipids, HP) and other degumming agents such as phosphoric acid, citric acid, or ...
Galectin-8 Induces Apoptosis in Jurkat T Cells by Phosphatidic Acid-mediated ERK1/2 Activation Supported by Protein Kinase A Down-regulation
(2009)
Galectins have been implicated in T cell homeostasis playing complementary pro-apoptotic roles. Here we show that galectin-8 (Gal-8) is a potent pro-apoptotic agent in Jurkat T cells inducing a complex phospholipase ...
Phospholipase D δ knock-out mutants re tolerant to severe drought stress
(Taylor & Francis, 2015-06)
Phospholipase D (PLD) is involved in different plant processes, ranging from responses to abiotic and biotic stress to plant development. Phospholipase Dδ (PLDδ) is activated in dehydration and salt stress, producing the ...
Phosphatidic acid increases Notch signalling by affecting Sanpodo trafficking during Drosophila sensory organ development
(Nature, 2020)
Organ cell diversity depends on binary cell-fate decisions mediated by the Notch signalling pathway
during development and tissue homeostasis. A clear example is the series of binary cell-fate decisions
that take place ...