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Novel aspects of parenchymal–mesenchymal interactions: from cell types to molecules and beyond
(Wiley, 2013-06)
Mesenchymal stem or stromal cells (MSCs) were initially isolated from the bone marrow and received their name on the basis of their ability to differentiate into multiple lineages such as bone, cartilage, fat and muscle. ...
The Antidiabetic Effect of Mesenchymal Stem Cells Is Unrelated to Their Transdifferentiation Potential But to Their Capability to Restore Th1/Th2 Balance and to Modify the Pancreatic Microenvironment
(2012)
Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease that results from cell-mediated autoimmune destruction of insulin-producing cells. In T1DM animal models, it has been shown that the systemic administration ...
Feasibility and safety of intrathecal transplantation of autologous bone marrow mesenchymal stem cells in horses
(Biomed Central Ltd, 2015-03-15)
Background: Recent studies have demonstrated numerous biological properties of mesenchymal stem cells and their potential application in treating complex diseases or injuries to tissues that have difficulty regenerating, ...
Mesenchymal stem cells with rhBMP-2 inhibits the growth of canine osteosarcoma cells
(BIOMED CENTRAL LTDLONDON, 2012)
Background: The bone morphogenetic proteins (BMPs) belong to a unique group of proteins that includes the growth factor TGF-beta. BMPs play important roles in cell differentiation, cell proliferation, and inhibition of ...
Osteogenic potential of mesenchymal cells derived from canine umbilical cord matrix co-cultured with platelet-rich plasma and demineralized bone matrix
(The Korean Society of Veterinary Science, 2015)
Canine mesenchymal cells (MSCs) derived from Wharton's jelly were co-cultured, then supplemented or not supplemented with platelet rich plasma (PRP) and demineralized bone matrix (DBM) to verify osteogenic differentiation. ...
Mesenchymal stem cell therapy for equine tendinitis
(2013-03-28)
Tendinitis is an important disease that leads to lameness and decreased performance in equine athletes and results in high costs associated with therapy due to a long recovery period and a high rate of recurrence. Although, ...
Differentiation of human mesenchymal stem cells through the natural matrix to neurospheres for cholinergic-like cells
(Oxford Univ Press, 2021-08-01)
Intrathecal Transplantation of Autologous and Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells in Dogs
(2021-01-01)
The route used in the transplantation of mesenchymal stem cells (MSCs) can directly affect the treatment success. The transplantation of MSCs via the intrathecal (IT) route can be an important therapeutic strategy for ...
MSC transplantation: a promising therapeutic strategy to manage the onset and progression of diabetic nephropathy
(2012)
complication is diabetic nephropathy (DN), a clinical syndrome associated with kidney damage and an increased risk of cardiovascular disease. Irrespective of the type of diabetes, DN follows a well-known temporal course. ...