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Genetic and epigenetic control of puberty
Puberty is a complex transitional phase in which reproductive capacity is achieved. There is a very wide variation in the age range of the onset of puberty, which follows a familial, ethnic, and sex pattern. The ...
Epigenetics regulates transcription and pathogenesis in the parasite Trichomonas vaginalis
(Wiley Blackwell Publishing, Inc, 2017-06)
Trichomonas vaginalis is a common sexually transmitted parasite that colonizes the human urogenital tract. Infections range from asymptomatic to highly inflammatory, depending on the host and the parasite strain. Different ...
Epigenetic patterns newly established after interspecific hybridization in natural populations of Solanum
(John Wiley & Sons Ltd, 2013-10)
Interspecific hybridization is known for triggering genetic and epigenetic changes, such as modifications on DNA methylation patterns and impact on phenotypic plasticity and ecological adaptation. Wild potatoes (Solanum, ...
Changes in micro RNA expression in a wild tuber-bearing Solanum species induced by 5-Azacytidine treatment
(Springer, 2012-03)
Phenotypic plasticity is often postulated as a principal characteristic of tuber-bearing wild Solanum species. The hypotheses to explore this observation have been developed based on the presence of genetic variation. In ...
Epigenetic variations in breast cancer progression to lymph node metastasis
(Springer, 2015-01)
Breast cancer is a heterogeneous disease characterized by the accumulation of genetic and epigenetic alterations that contribute to the development of regional and distant metastases. Lymph node metastasis (LNM) status is ...
Genetic variation in long noncoding RNAs and the risk of nonalcoholic fatty liver disease
(Impact Journals LLC, 2017-02-11)
The human transcriptome comprises a myriad of non protein-coding RNA species, including long noncoding RNAs (lncRNAs), which have a remarkable role in transcriptional and epigenetic regulation. We hypothesized that variants ...
Epigenetic consequences of interploidal hybridisation in synthetic and natural interspecific potato hybrids
(Wiley Blackwell Publishing, Inc, 2019-06)
Interploidal hybridisation can generate changes in plant chromosome numbers, which might exert effects additional to the expected due to genome merger per se (i.e., genetic, epigenetic and phenotypic novelties).Wild potatoes ...