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Modelagem, integração e análise exploratória de dados públicos de mirtrons
(Universidade Tecnológica Federal do ParanáCornelio ProcopioBrasilPrograma de Pós-Graduação em BioinformáticaUTFPR, 2018-09-14)
MicroRNAs (miRNAs) are the most studied non-coding RNA class in literature. This small ncRNA class acts in cellular control of several biological processes, through its post-transcriptional regulatory role in messenger RNA ...
Auxin and Cellular Elongation
(American Society Of Plant Biologist, 2016-03)
Auxin is a crucial growth regulator in plants. However, a comprehensive understanding of how auxin induces cell expansion is perplexing, because auxin acts in a concentration- and cell type-dependent manner. Consequently, ...
Cellular alterations induced by heat stress in bovine embryosAlterações celulares induzidas pelo estresse térmico em embriões bovines
(2013-01-01)
Adverse environmental conditions such as high temperature and humidity increase internal body temperature (hyperthermia) of lactating dairy cows resulting in heat stress and decreased pregnancy rates. Embryonic susceptibility ...
MicroRNA-1254 contributes to the controlling of pro-fibrogenic environment in LX-2 cells by modulating SMAD3 and wound repair: new insights in hepatic fibrosis
(Wiley-Blackwell, 2019-03-01)
Hepatic fibrosis and its end-stage cirrhosis have increased worldwide, and, despite all the efforts, no successful therapy is available. More recently, the heptapeptide angiotensin-(1-7) [ang-(1-7)] was reported to be able ...
Physiological implications of trehalose in the ectomycorrhizal fungus Pisolithus sp. under thermal stress
(Journal of Thermal Biology, 2018)
Mir-190b negatively contributes to the Trypanosoma cruzi-infected cell survival by repressing PTEN protein expression
(Fundaco Oswaldo Cruz, 2015-12-01)
Chagas disease, which is caused by the intracellular protozoan Trypanosoma cruzi, is a serious health problem in Latin America. The heart is one of the major organs affected by this parasitic infection. The pathogenesis ...
Role of the Renin-Angiotensin-Aldosterone System beyond Blood Pressure Regulation: Molecular and Cellular Mechanisms Involved in End-Organ Damage during Arterial Hypertension.
(2016)
Arterial hypertension is a common condition worldwide and an important predictor of several complicated diseases. Arterial hypertension can be triggered by many factors, including physiological, genetic, and lifestyle ...
A novel function for CUGBP2 in controlling the pro-inflammatory stimulus in H9c2 cells: Subcellular trafficking of messenger molecules
(2013-06-07)
Accumulating evidence demonstrates that chronic inflammation plays an important role in heart hypertrophy and cardiac diseases. However, the fine-tuning of cellular and molecular mechanisms that connect inflammatory process ...