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Mostrando ítems 21-30 de 148
Avaliação da atividade antitumoral de derivados do tiazol, tiazolinonas e tiossemicarbazonas
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Ciencias Farmaceuticas, 2019)
Importance of mevalonate pathway lipids on the growth and survival of primary and metastatic gastric carcinoma cells
(2021)
Purpose: This preclinical study aims to determine the effect of drugs that alter isoprenoids and cholesterol metabolism in the homeostasis of gastric carcinoma cell lines in the search for new therapeutic targets for stomach ...
Ru-90@bio-MOF-1: A ruthenium(II) metallodrug occluded in porous Zn-based MOF as a strategy to develop anticancer agents
(2021-05-01)
One of the major challenges in the field of biomedicine is to use biocompatible carriers to achieve efficient drug delivery in the body. Most of the existing carriers have shown poor loading and rapid drug release. In this ...
Síntese e avaliação da atividade antitumoral de heterocíclicos furânicos, triazólicos e quinolínicos contendo o núcleo naftoquinona
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Quimica, 2017)
Differential Antitumor Effects of IgG and IgM Monoclonal Antibodies and Their Synthetic Complementarity-Determining Regions Directed to New Targets of B16F10-Nex2 Melanoma Cells
(NEOPLASIA PRESS, 2010)
Malignant melanoma has increased incidence worldwide and causes most skin cancer-related deaths. A few cell surface antigens that can be targets of antitumor immunotherapy have been characterized in melanoma. This is an ...
Avaliação das atividades antitumoral e antioxidante in vitro de extratos de Libidibia ferrea em células de câncer colorretal
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE, 2017-06-23)
Colorectal cancer is noted for being one of the most frequent of tumors, with expressive morbidity and mortality rates. In new drug discovery, plants stand out as a source capable of yielding safe and high-efficiency ...
Carvacrol: An in silico approach of a candidate drug on HER2, PI3Kα, mTOR, HER-α, PR, and EGFR receptors in the breast cancer
(Hindawi Limited, 2020-01-01)
Carvacrol is a phenol monoterpene found in aromatic plants specially in Lamiaceae family, which has been evaluated in an experimental model of breast cancer. However, any proposed mechanism based on its antitumor effect ...
Development and therapeutic potential of vasopressin synthetic analog [V4Q5]dDAVP as a novel anticancer agent
(Elsevier Academic Press Inc., 2020-01)
Since its discovery, arginine vasopressin (AVP) was subjected to several modifications with the aim of obtaining novel derivatives with increased potency and selectivity for biomedical use. Desmopressin (dDAVP) is a first ...