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Amnesia of inhibitory avoidance by scopolamine is overcome by previous open-field exposure
(Cold Spring Harbor Lab Press, 2014-11)
The muscarinic cholinergic receptor (MAChR) blockade with scopolamine either extended or restricted to the hippocampus, before or after training in inhibitory avoidance (IA) caused anterograde or retrograde amnesia, ...
Papel de mTOR, BDNF, AMPAR E NMDAR na reconsolidação da memória de extinção
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM PSICOBIOLOGIA, 2019-03-15)
Memory reactivation can induce two apparently competing processes,
namely extinction and reconsolidation. Extinction involves reduction of a
previously acquired response to a stimulus through formation of a new memory
trace. ...
Estudo do envolvimento do córtex perirrinal na reconsolidação da memória de reconhecimento de objetos
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM NEUROCIÊNCIAS, 2019-03-14)
Consolidated memories can become labile when reactivated and, to persist, must
undergo a protein synthesis-dependent restabilization process called
reconsolidation. The perirhinal cortex (PER) regulates the flow of ...
Persistence of long-term memory storage: new insights into its molecular signatures in the hippocampus and related structures
(Springer, 2010-11)
Although much is known about long-term memory (LTM) consolidation, what puts the "long" in LTM is the exclusive feature of persisting over time. However, until recently the molecular mechanisms underneath memory persistence ...
Reconsolidação da memória de extinção: análise farmacológica, bioquímica e molecular
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2015)
Background : Therapies based on the impairment of memory reconsolidation or the enhancement of extinction learning offer the possibility of diminishing the impact caused by the persistent recollection of traumatic events. ...
Análise neurofarmacológica e neuroquímica da expressão de memórias espaciais
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2012)
Memories are not stored in its final form immediately after the acquisition. They undergo a long stabilization process known as consolidation. Consolidated memories can become labile again after the retrieval and susceptible ...
A melhora da reconsolidação da memória induzida por espermidina envolve a proteína cinase dependente de cálcio
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2015-07-21)
The reactivation of a memory results in its destabilization, requiring a process of
memory reconsolidation to maintain it. Spermidine is an endogenous aliphatic amine
with polycationic structure that modulates ...