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Telomere length and its relationship with chronic diseases - New perspectives for periodontal research
(2013-02-01)
Objective: The ageing process is accompanied by a variety of cellular modifications, and telomere shortening is a common finding. Large epidemiological studies have reported an association between shorter telomere length ...
Consequences of acute oxidative stress in Leishmania amazonensis: From telomere shortening to the selection of the fittest parasites
(2017-01-01)
Leishmaniasis is a spectrum of diseases caused by parasites of the genus Leishmania that affects millions of people around the world. During infection, the parasites use different strategies to survive the host's defenses, ...
Seasonal Variation of Peripheral Blood Leukocyte Telomere Length in Costa Rica: A Population-Based Observational Study
(2014)
ABSTRACT: Objectives: Peripheral blood leukocyte telomere length (LTL) is increasingly being used as a biomarker of aging, but its natural variation in human populations is not well understood. Several other biomarkers ...
Seasonal Variation of Peripheral Blood Leukocyte Telomere Length in Costa Rica: A Population-Based Observational Study
(2014)
ABSTRACT: Objectives: Peripheral blood leukocyte telomere length (LTL) is increasingly being used as a biomarker of aging, but its natural variation in human populations is not well understood. Several other biomarkers ...
Telomere protein complexes and their role in lymphoid malignancies
(Frontiers in bioscience, 2017-01)
Telomeres are highly regulated and dynamic complexes that protect the genomic DNA and prevent the end of linear chromosomes from being misrecognized as a broken DNA. Due to the end replication problem, telomeres of somatic ...
Telomere-Related Disorders in Fetal Membranes Associated With Birth and Adverse Pregnancy Outcomes
(2020-10-02)
Telomere disorders have been associated with aging-related diseases, including diabetes, vascular, and neurodegenerative diseases. The main consequence of altered telomere is the induction of the state of irreversible cell ...
Differential expression of non-shelterin genes associated with high telomerase levels and telomere shortening in plasma cell disorders
(Public Library of Science, 2015-09-14)
Telomerase, shelterin proteins and various interacting factors, named non-shelterin proteins, are involved in the regulation of telomere length (TL). Altered expression of any of these telomere-associated genes can lead ...
On Microgravity and Biological Process
(Hikari, 2019-09)
Certain biological processes could be directly related to physics, such as telomere shortening and the activation of the telomerase enzyme. Telomere shortening is a well-known process that sets the pace of life in every ...