Buscar
Mostrando ítems 11-20 de 189
Role of α-melanocyte stimulating hormone and melanocortin 4 receptor in brain inflammation
(Elsevier Science Inc, 2008-10)
Inflammatory processes contribute widely to the development of neurodegenerative diseases. The expression of many inflammatory mediators was found to be increased in central nervous system (CNS) disorders suggesting that ...
Expression of melanocortin receptors mRNA, and direct effects of ACTH on steroids secretion in the bovine ovary
(Elsevier Science Inc, 2011-09)
Melanocortin receptors (MCRs) are involved in physiological responses to ACTH, as well as to α-, β- and γ-melanocyte-stimulating hormone (α-, β- and γ-MSH). Their expression has previously been analyzed in various bovine ...
Melanocortin 4 receptor activation inhibits presynaptic N-type calcium channels in amygdaloid complex neurons
(Wiley Blackwell Publishing, Inc, 2014-06)
The melanocortin 4 receptor (MC4R) is a G protein-coupled receptor involved in food intake and energy expenditure regulation. MC4R activation modifies neuronal activity but the molecular mechanisms by which this regulation ...
Sistema leptina-melanocortinas en la regulación de la ingesta y el peso corporal
(2009)
Obesity is a multifactorial disease that is rarely associated to single gene defects. However, due to their direct cause-effect relationships, those genetic defects that cause some forms of monogenic obesity are relevant ...
Effect of the melanocortin-3 receptor Thr6Lys and Val81Ile genetic variants on body composition and substrate oxidation in Chilean obese children
(2011)
Mice genetically deficient in the melanocortin-3 receptor gene are characterized by normal body weight, increased body fat, mild hypophagia, reduced locomotor activity, and increased respiratory quotient compared with ...
Memory impairment induced by IL-1beta is reversed by alpha-MSH through central melanocortin-4 receptors
(Academic Press Inc Elsevier Science, 2009-12)
Interleukin-1beta (IL-1beta) significantly influences memory consolidation. Treatments that raise the level of IL-1beta in the brain, given after training, impair contextual fear conditioning. The melanocortin alpha-MSH ...
Plumage variation in the Planalto Woodcreeper (Dendrocolaptes platyrostris) and the melanocortin-1 receptor gene (MC1R)
(Soc Brasileira Ornitologia, 2013-03)
The Planalto Woodcreeper (Dendrocolaptes platyrostris) presents “pale” and “dark” plumage variants, which are distributed throughout the Cerrado and Caatinga, and throughout the Atlantic Forest, respectively. To understand ...
Astrocytes: New Targets of Melanocortin 4 Receptor Actions
(BioScientifica, 2013-07-23)
Astrocytes exert a wide variety of functions with paramount importance in brain physiology. After injury or infection, astrocytes become reactive and they respond by producing a variety of inflammatory mediators that help ...