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Gap junctions and communication within the nervous system
(Botucatu, 2008)
Gap junctions are sites on the cellular membrane with intercellular channels build up by twelve protein subunits called connexins. Each connected cell contributes with a hemichannel made up by six connexins subunits. This ...
New insights on the role of connexins and Gap Junctions Channels in adipose tissue and Obesity
(MDPI, 2021)
Due to the inability to curb the excessive increase in the prevalence of obesity and overweight, it is necessary to comprehend in more detail the factors involved in the pathophysiology and to appreciate more clearly the ...
Control of intracellular movement of connexins by E-cadherin in murine skin papilloma cells
(Academic Press IncSan DiegoEUA, 2001)
The absence of dysferlin induces the expression of functional connexin-based hemichannels in human myotubes
(2016)
Background: Mutations in the gene encoding for dysferlin cause recessive autosomal muscular dystrophies called dysferlinopathies. These mutations induce several alterations in skeletal muscles, including, inflammation, ...
Maternal diabetes induces FoxO1 and connexin 43 alterations in the heart of the developing embryo
(Elsevier, 2019)
Background: Maternal diabetes affects the embryonic, fetal and perinatal development and programs metabolic and cardiovascular alterations in the adult offspring. We recently reported cardiovascular alterations related to ...
Diminished angiogenesis in the cornea of mice with heterologous deletion of Connexin 43 gene (Gjal1)
(Botucatu, 2010)
Angiogenesis is involved in several physiological and pathological processes, and the proliferation of endothelial cells is a central event in the generation of new blood vessels. Gap junctions (GJ) are membrane structures ...