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Actin-binding proteins and signalling pathways associated with the formation and maintenance of dendritic spines [Participación de las proteínas de unión a la actina y vías de señalización asociadas a la formación y mantenimiento de las espinas dendríticas]
(2012)
Introduction: Dendritic spines are the main sites of excitatory synaptic contacts. Moreover, they present plastic responses to different stimuli present in synaptic activity or damage, ranging from an increase or decrease ...
Dynamin-2 mutations linked to Centronuclear Myopathy impair actin-dependent trafficking in muscle cells
(2017)
Dynamin-2 is a ubiquitously expressed GTP-ase that mediates membrane remodeling. Recent findings indicate that dynamin-2 also regulates actin dynamics. Mutations in dynamin-2 cause dominant centronuclear myopathy (CNM), a ...
Isolation of galectin-1 from human platelets: its interaction with actin
(Springer, 2012-01)
Galectins are a family of animal lectins defined by their β-galactoside-binding specificity and a consensus sequence in their carbohydrate-recognition domain. Galectin-1 (Gal-1) is expressed as a non-covalently linked ...
Thermodynamic origin of cooperativity in actomyosin interactions: The coupling of short-range interactions with actin bending stiffness in an Ising-like model
(AMER PHYSICAL SOC, 2009)
We present Monte Carlo simulations for a molecular motor system found in virtually all eukaryotic cells, the acto-myosin motor system, composed of a group of organic macromolecules. Cell motors were mapped to an Ising-like ...
Nuclear actin polymerization from faster growing ends in the initial activation of hox gene transcription Are nuclear speckles involved?
(Landes Biosciences, 2014-01)
The HoxB cluster expression is activated by retinoic acid and transcribed in a collinear manner. The DNA-binding Pknox1-Pbx1 complex modulates Hox protein activity. Here, NT2-D1 teratocarcinoma cells -a model of Hox gene ...
Nuclear actin polymerization from faster growing ends in the initial activation of hox gene transcription: Are nuclear speckles involved?
(Taylor and Francis Inc., 2014-01-06)
The HoxB cluster expression is activated by retinoic acid and transcribed in a collinear manner. The DNA-binding Pknox1-Pbx1 complex modulates Hox protein activity. Here, NT2-D1 teratocarcinoma cells -a model of Hox gene ...