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Involvement of Lysophosphatidic Acid, Sphingosine 1-Phosphate and Ceramide 1-Phosphate in the Metabolization of Phosphatidic Acid by Lipid Phosphate Phosphatases in Bovine Rod Outer Segments
(Springer/Plenum Publishers, 2008-07)
The aim of the present research was to evaluate the generation of [2-3H]diacylglycerol ([2-3H]DAG) from [2-3H]-Phosphatidic acid ([2-3H]PA) by lipid phosphate phosphatases (LPPs) at different concentrations of lysophosphatidic ...
Identification and physiological characterization of phosphatidic acid phosphatase enzymes involved in triacylglycerol biosynthesis in Streptomyces coelicolor
(Biomed Central, 2013-01)
BACKGROUND: Phosphatidic acid phosphatase (PAP, EC 3.1.3.4) catalyzes the dephosphorylation of phosphatidate yielding diacylglycerol (DAG), the lipid precursor for triacylglycerol (TAG) biosynthesis. Despite the importance ...
Phosphatidic acid and diacylglycerol generation is regulated by insulin in cerebral cortex synaptosomes from adult and aged rats
(Veterinary and Human Toxicology, 2005-07)
Insulin receptor associated with the cerebral cortex (CC) has been shown to be involved in brain cognitive functions. Furthermore, deterioration of insulin signaling has been associated with age-related brain degenera tion. ...
Characterization of key enzymes involved in triacylglycerol biosynthesis in mycobacteria
(Scientific Reports, 2022)
Nitric oxide triggers phosphatidic acid accumulation via phospholipase D during auxin-induced adventitious root formation in cucumber
(American Society of Plant Biologist, 2008-07)
Auxin and nitric oxide (NO) play fundamental roles throughout plant life. NO is a second messenger in auxin signal transductionleading to root developmental processes. The mechanisms triggered by auxin and NO that direct ...
Age-related changes in the metabolization of phosphatidic acid in cerebral cortex synaptosomes
(Elsevier Science Inc, 2009-08-15)
In this study, phosphatidic acid (PA) metabolization is found to generate diacylglycerol (DAG), monoacylglycerol (MAG) and glycerol by the sequential action of lipid phosphate phosphatase (LPP), diacylglycerol lipase (DAGL), ...
Galectin-8 induces apoptosis in jurkat t cells by phosphatidic acid-mediated erk1/2 activation supported by protein kinase a down-regulation
(AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2009)
Phosphatidic acid induces ligand-independent epidermal growth factor receptor endocytic traffic through pde4 activation
(AMERICAN SOCIETY FOR CELL BIOLOGY, 2010)