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Mostrando ítems 11-20 de 66
Biochemical-molecular markers in unilateral ureteral obstruction
(Instituto de Histología y Embriología, 2007-12)
Congenital obstructive nephropathy is the primary cause of end-stage renal disease in chil dren. Rapid diagnosis and initiation of the treatment are vital to preserve function and/or to slow down renal injury. Obstructive ...
Heart Remodeling and Ischemia–Reperfusion Arrhythmias Linked to Myocardial Vitamin D Receptors Deficiency in Obstructive Nephropathy Are Reversed by Paricalcitol
(Sage Publications, 2014-06)
Cardiovascular disease is often associated with chronic kidney disease and vice versa; myocardial vitamin D receptors (VDRs) are among the probable links between the 2 disorders. The vitamin D receptor activator paricalcitol ...
Antiarrhythmic effect linked to melatonin cardiorenal protection involves AT1 reduction and Hsp70-VDR increase
(Wiley Blackwell Publishing, Inc, 2018-11)
Lethal ventricular arrhythmias increase in patients with chronic kidney disease that suffer an acute coronary event. Chronic kidney disease induces myocardial remodeling, oxidative stress, and arrhythmogenesis. A manifestation ...
Role of endogenous nitric oxide in unilateral ureteropelvic junction obstruction in children
(Nature Publishing Group, 2003-12)
Background. Obstructive nephropathy leads to tubulointerstitial fibrosis and loss of renal function. Nitric oxide has been shown to have antifibrotic properties. We examined nitric oxide synthase (NOS) activity and expression ...
CKD and CKDu in northern Peru: a cross-sectional analysis under the DEGREE protocol
(BioMed Central, 2021)
BACKGROUND: This study estimated the prevalence and risk factors for decreased estimated glomerular filtration rate (eGFR) in those without known hypertension, type 2 diabetes mellitus, or heavy proteinuria as a surrogate ...
N-acetylcysteine protects against renal injury following bilateral ureteral obstruction
(OXFORD UNIV PRESS, 2008)
Background. Obstructive nephropathy decreases renal blood flow (RBF) and glomerular filtration rate (GFR), causing tubular abnormalities, such as urinary concentrating defect, as well as increasing oxidative stress. This ...
Losartan modulation on NOS isoforms and COX-2 expression in early renal fibrogenesis in unilateral obstruction
(Elsevier, 2004-12)
BACKGROUND: Angiotensin II plays a central role in the initiation of renal fibrogenesis at a very early stage leading to a rapid progression in unilateral ureteral obstruction (UUO). We examined the effect of an angiotensin ...