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Direct effects of ethanol on neuronal differentiation: An in vitro analysis of viability and morphology
(Pergamon-Elsevier Science Ltd, 2016-10)
The deleterious effects of ethanol (EtOH) on the brain have been widely described, but its effects on theneuronal cytoskeleton during differentiation have not yet been firmly established. In this context, ouraim was to ...
Iron and glutathione at the crossroad of redox metabolism in neurons
(2006)
Neurons, as non-dividing cells, encounter a myriad of stressful conditions throughout their lifespan. In
particular, there is increasing evidence that iron progressively accumulates in the brain with age and that ...
c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling
(2019)
During the development of the sympathetic nervous system, signals from tropomyosin-related kinase receptors (Trks) and p75 neurotrophin receptors (p75) compete to regulate survival and connectivity. During this process, ...
1-42 B-amyloid peptide (AB1-42) requires PDK1/nPKCs/Rac 1 pathway to induce neuronal death
(Nature Publishing Group, 2013-01)
1–42 β-Amyloid (Aβ1–42) peptide is a key molecule involved in the development of Alzheimer's disease. Some of its effects are manifested at the neuronal morphological level. These morphological changes involve loss of ...
S100B alters neuronal survival and dendrite extension via RAGE-mediated NF-κB signaling
(Wiley Blackwell Publishing, Inc, 2011-04)
S100B is a soluble protein secreted by astrocytes that exerts pro-survival or pro-apoptotic effects depending on the concentration reached in the extracellular millieu. The S100B receptor termed RAGE (for receptor for ...
GM-1 ganglioside treatment reduces motoneuron death after ventral root avulsion in adult rats
(Elsevier Sci Ireland LtdClareIrlanda, 2000)
Fluoro-Jade, but not Fluoro-Jade B, stains non-degenerating cells in brain and retina of embryonic and neonatal rats
(Elsevier Science BvAmsterdamHolanda, 2004)
An alkaloid extract obtained from Phlegmariurus Saururus induces neuroprotection after status epilepticus
(Elsevier Gmbh, 2017-10)
Background The brain is exposed to many excitotoxic insults that can lead to neuronal damage. Among these, Epilepsy is a neurological disease that affects a large percentage of world population and is commonly associated ...
Efeitos da eliminação de neurônios infragranulares sobre a especificação de neurônios supragranulares do córtex cerebral
(Universidade Federal do Rio Grande do NorteBRUFRNPrograma de Pós-Graduação em NeurocienciasNeurobiologia Celular e Molecular; Neurobiologia de Sistemas e Cognição; Neurocomputação Neuroengen, 2012-08-10)
The cerebral cortex of mammals is histologically organized into different layers of
excitatory neurons that have distinct patterns of connections with cortical or subcortical
targets. During development, these cortical ...