Buscar
Mostrando ítems 11-20 de 157
Evaluating the efficacies of Maximum Tolerated Dose and metronomic chemotherapies: A mathematical approach
(Elsevier B.V., 2016-08-15)
We present a mathematical model based on partial differential equations that is applied to understand tumor development and its response to chemotherapy. Our primary aim is to evaluate comparatively the efficacies of two ...
On the synchronization of two metronomes and their related dynamics
(Universidade Estadual Paulista (Unesp), 2017-06-05)
Nesta tese são investigadas, teórica e experimentalmente, a sincronização em fase e a sincronização em anti-fase de dois metrônomos oscilando sobre uma base móvel, a partir de um modelo aqui proposto. Uma descrição do ...
Muscarinic Receptors as Targets for Metronomic Therapy in Breast Cancer.
(Bentham Science Publishers, 2016-01)
BACKGROUND: It is actually known that acetylcholine works as a signaling molecule in non-neuronal cells and tissues, in addition to its neuronal function as neurotransmitter. It can act on two types of receptors nicotinic ...
Therapeutic efficacy of metronomic chemotherapy with cyclophosphamide and doxorubicin on murine mammary adenocarcinomas
(Oxford University Press, 2013-05)
Background: Metronomic chemotherapy (MCT) refers to the chronic and equally spaced administration of low doses of different chemotherapy drugs, without extended rest periods. Herein, we investigated the therapeutic efficacy ...
Association between baseline VEGF/sVEGFR-2 and VEGF/TSP-1 ratios and response to metronomic chemotherapy using cyclophosphamide and celecoxib in patients with advanced breast cancer
(Indian Cancer Society and Indian Society of Oncology, 2018)
Metronomic therapy with cyclophosphamide induces rat lymphoma and sarcoma regression, and is devoid of toxicity
(Oxford University Press, 2012)
Safety and therapeutic effect of metronomic chemotherapy with cyclophosphamide and celecoxib in advanced breast cancer patients
(Future Medicine, 2013-03)
Metronomic chemotherapy (MCT), the chronic administration, at regular intervals, of low doses of chemotherapeutic drugs without extended rest periods, allows chronic treatment with therapeutic efficacy and low toxicity. ...
The metronomic combination of paclitaxel with cholinergic agonists inhibits triple negative breast tumor progression. Participation of M2 receptor subtype
(Public Library of Science, 2020-09)
Triple negative tumors are more aggressive than other breast cancer subtypes and there is a lack of specific therapeutic targets on them. Since muscarinic receptors have been linked to tumor progression, we investigated ...
Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24–25 June 2014, Milan
(European Institute of Oncology.OECI, 2018)