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Three Prime Repair Exonuclease 1 (TREX1) expression correlates with cervical cancer cells growth in vitro and disease progression in vivo
(Nature, 2019)
Alterations in specific DNA damage repair mechanisms in the presence of human papillomavirus (HPV) infection have been described in different experimental models. However, the global effect of HPV on the expression of genes ...
A exonuclease XRNA e o metabolismo de mRNA em Trypanosoma cruzi
(2015)
A regulação da expressão gênica em tripanossomatídeos ocorre majoritariamente pelo controle de eventos pós-transcricionais. Dentre estes, mudanças na estabilidade e acesso dos mRNAs à maquinaria de tradução estão diretamente ...
Molecular and cytogenetic analysis of the telomeric (TTAGGG)n repetitive sequences in the Nile tilapia, Oreochromis niloticus (Teleostei: Cichlidae)
(2002-03-01)
The majority of chromosomes in Oreochromis niloticus, as with most fish karyotyped to date, cannot be individually identified owing to their small size. As a first step in establishing a physical map for this important ...
Molecular and cytogenetic analysis of the telomeric (TTAGGG)n repetitive sequences in the Nile tilapia, Oreochromis niloticus (Teleostei: Cichlidae)
(2002-03-01)
The majority of chromosomes in Oreochromis niloticus, as with most fish karyotyped to date, cannot be individually identified owing to their small size. As a first step in establishing a physical map for this important ...
Accuracy of replication in the polymerase chain reaction. Comparison between Thermotoga maritima DNA polymerase and Thermus aquaticus DNA polymerase
(Associação Brasileira de Divulgação Científica, 1998-10-01)
For certain applications of the polymerase chain reaction (PCR), it may be necessary to consider the accuracy of replication. The breakthrough that made PCR user friendly was the commercialization of Thermus aquaticus (Taq) ...
Sofosbuvir terminated RNA is more resistant to SARS‐CoV‐2 proofreader than RNA terminated by Remdesivir
SARS-CoV-2 is responsible for COVID-19, resulting in the largest pandemic in over a hundred years.
After examining the molecular structures and activities of hepatitis C viral inhibitors and comparing
hepatitis C virus ...
Rad51 prevents Mre11-dependent degradation and excessive primpol-mediated elongation of nascent DNA after UV irradiation
(National Academy Of Sciences, 2015-12)
After UV irradiation, DNA polymerases specialized in translesion DNA synthesis (TLS) aid DNA replication. However, it is unclear whether other mechanisms also facilitate the elongation of UV-damaged DNA. We wondered if ...
Caracterização de um plano plasmídio conjugativo de mycobacterium avium
(Universidade Federal de São Paulo (UNIFESP), 2016-03-30)
Objective: Characterization of the pMA100 conjugative plasmid from Mycobacterium avium, identifying its replication origin and conjugation mechanism. Material and Methods: To identify and describe the main components of ...