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Replacement of the V3 Domain in the Surface Subunit of the Feline Immunodeficiency Virus Envelope Glycoprotein with the Equivalent Region of a T Cell-Tropic Human Immunodeficiency Virus Type 1 Results in a Chimeric Surface Protein That Efficiently Binds to CXCR4
(Universidad de Belgrano - Facultad de Ciencias Exactas y Naturales - Proyectos de Investigación, 2014)
Feline immunodeficiency virus (FIV) and the T cell-tropic strains of human immunodeficiency virus type 1 (HIV-1) share the use of the chemokine receptor CXCR4 for cell entry. To study this process further we developed a ...
In vitro binding of simian immunodeficiency virus matrix protein to the cytoplasmic domain of the envelope glycoprotein
(Universidad de Belgrano - Facultad de Ciencias Exactas y Naturales - Proyectos de Investigación, 2008)
Incorporation of the envelope (Env) glycoprotein into budding virions is a key step in the replication cycle of lentiviruses. Previously, we provided
genetic and biochemical evidence indicating that Env packaging into ...
Clonagem e expressão da glicoproteína transmembrana do retrovírus HTLV-1 em células de mamíferos
(2006-03-01)
The retrovirus HTLV-1 is the etiological agent of the adult T-cell leukemia and HTLV-1 associated myelopathy/tropical spastic paraparesis. The proviral genome has 9,032 base pairs, showing regulatory and structural genes. ...
Clonagem e expressão da glicoproteína transmembrana do retrovírus HTLV-1 em células de mamíferos
(2006-03-01)
The retrovirus HTLV-1 is the etiological agent of the adult T-cell leukemia and HTLV-1 associated myelopathy/tropical spastic paraparesis. The proviral genome has 9,032 base pairs, showing regulatory and structural genes. ...
Discovery of a Potent and Selective Chikungunya Virus Envelope Protein Inhibitor through Computer-Aided Drug Design
(American Chemical Society Inc, 2021-05)
The worldwide expansion of chikungunya virus (CHIKV) into tropical and subtropical areas in the last 15 years has posed a currently unmet need for vaccines and therapeutics. The E2-E1 envelope glycoprotein complex binds ...
Low pH protection in the exocytic pathway: a role of the hantavirus Gn glycoprotein in the fusion activity of Gc?
(2015)
Introduction: Virus-cell membrane fusion represents a crucial step in the infection of cells by enveloped
viruses. For this process, hantaviruses employ their Gc envelope glycoprotein after uptake into the endosomal
pathway. ...
The cloning of the virus envelope glycoprotein F of canine distemper virus expressed in Pichia pastoris
(Academic Press Ltd - Elsevier Science Ltd, 2020-05)
Canine distemper virus (CDV) is a pathogen which affects members of the Canidae family, causing an acute, often fatal, systemic disease. CDV is an RNA virus of the family Paramyxoviridae that contains two envelope ...