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Desenvolvimento de métodos analíticos qualitativos para a análise de darunavir comprimidos
(2013-06-27)
Darunavir is a protease inhibitor used in the treatment of HIV infection. It is a pillar of the drug cocktail for patients diagnosed with the virus. Quality control in the pharmaceutical industry, to verify the content of ...
Desenvolvimento de métodos analíticos qualitativos para a análise de darunavir comprimidos
(2013-06-27)
Darunavir is a protease inhibitor used in the treatment of HIV infection. It is a pillar of the drug cocktail for patients diagnosed with the virus. Quality control in the pharmaceutical industry, to verify the content of ...
Stability study of darunavir ethanolate tablets applying a new stability-indicating HPLC method
(2013)
Chemical and physical degradation of drugs may result in altered therapeutic efficacy and even toxic effects. Therefore, the aim of this work was to study the stability of darunavir and to develop and validate a liquid ...
Lack of antiviral activity of darunavir against SARS-CoV-2
Objectives: Given the high need and the absence of specific antivirals for treatment of COVID-19 (the
disease caused by severe acute respiratory syndrome-associated coronavirus-2 [SARS-CoV-2]), human
immunodeficiency ...
Comparative study over methods developed for quantification of darunavir in tablets by environmental friendly infrared and capillary electrophoretic techniques
(2015)
Darunavir, a protease inhibitor used in the treatment of HIV infection, presents few methods for its determination in pharmaceuticals. Infrared (IR) spectroscopy offers the possibility of obtaining spectra relatively ...
Development and validation of infrared spectroscopy method for the determination of darunavir in tabets
(Scientific and Academic Publishing, 2016)