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Casearin X exhibits cytotoxic effects in leukemia cells triggered by apoptosis
(Elsevier B.V., 2010-12-05)
Clerodane diterpenes have demonstrated cytotoxic, antiplasmodial and anti-ulcer properties. In the present work, we determined the cytotoxic effect of casearin L (Cas L), O (Cas O) and X (Cas X) and (-)-hardwickiic acid ...
Preclinical anticancer effectiveness of a fraction from Casearia sylvestris and its component Casearin X: in vivo and ex vivo methods and microscopy examinations
(Elsevier B.V., 2016-06-20)
Ethnopharmacological relevance: Casearia sylvestris (Salicaceae) is found in South America and presents antiulcerogenic, cytotoxic, antimicrobial, anti-inflammatory and antihypertensive activities. Aim of the study: To ...
Acetylated DNA-damaging clerodane diterpenes from Casearia sylvestris
(Elsevier B.V., 2014)
Assessment of the chemopreventive effect of casearin B, a clerodane diterpene extracted from Casearia sylvestris (Salicaceae)
(2013-03-01)
Studies have shown that Casearia sylvestris compounds protect DNA from damage both in vitro and in vivo. Complementarily, the aim of the present study was to assess the chemopreventive effect of casearin B (CASB) against ...
Assessment of the chemopreventive effect of casearin B, a clerodane diterpene extracted from Casearia sylvestris (Salicaceae)
(2013-03-01)
Studies have shown that Casearia sylvestris compounds protect DNA from damage both in vitro and in vivo. Complementarily, the aim of the present study was to assess the chemopreventive effect of casearin B (CASB) against ...
Anti-inflammatory action of ethanolic extract and clerodane diterpenes from Casearia sylvestris
(Soc Brasileira Farmacognosia, 2017-07-01)
The present study aimed to investigate the anti-inflammatory activity of ethanolic extract from Casearia sylvestris Sw., Salicaceae, leaves and to identify the compounds responsible for this activity. The ethanolic extract ...
Casearin X exhibits cytotoxic effects in leukemia cells triggered by apoptosis
(Elsevier B.V., 2014)
Natural membranes of Hevea brasiliensis latex as delivery system for Casearia sylvestris leaf components
(Soc Brasileira Farmacognosia, 2018-01-01)
Natural latex from Hevea brasiliensis (Wild. ex A.Juss) Miill.Arg., Euphorbiaceae, showed angiogenic action and Casearia sylvestris Sw., Salicaceae, leaf derivatives presented anti-inflammatory and wound healing activities. ...
In Vitro Schistosomicidal Activities of the Leaf Extracts from Casearia sylvestris Varieties
(2022-02-01)
Schistosomiasis, a tropical disease caused by flatworms, may affect the liver, spleen, bladder, and intestine. Casearia sylvestris Swartz, a medicinal plant, displays antiprotozoal, antimicrobial, antifungal, and antiulcer ...