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NNAlign-MA; MHC peptidome deconvolution for accurate MHC binding motif characterization and improved t-cell epitope predictions
(American Society for Biochemistry and Molecular Biology, 2019-10)
The set of peptides presented on a cell´s surface by MHC molecules is known as the immunopeptidome. Current mass spectrometry technologies allow for identification of large peptidomes, and studies have proven these data ...
Biogeography, ecology, and spatial patterns of patagonian lizards
(Springer Nature Switzerland AG, 2020)
Patagonia has a great diversity of lizards, including 6 families, 11 genera and 163 species. The majority of this diversity with documented geographical records corresponds to the Liolaemidae family (Phymaturus and Liolaemus). ...
Phylogenomics, CAZyome and core secondary metabolome of Streptomyces albus species
(Springer Heidelberg, 2021-09-26)
A phylogenomic study conducted with different bioinformatic tools such as TYGS, REALPHY and AAI comparisons revealed a high AQ1 rate of misidentified Streptomyces albus genomes in GenBank. Only 9 of the 18 annotated genomes ...
Predicting the effect of steroids on membrane biophysical properties based on the molecular structure
(Elsevier, 2012-03)
The relationship between sterol structure and the resulting effects on membrane physical properties is still unclear, owing to the conflicting results found in the current literature. This study presents a multivariate ...
Molecular variability of watermelon mosaic virus isolates from Argentina
(Springer, 2020-04)
Watermelon mosaic virus (WMV) is an economically important virus of cucurbit crops in Argentina. The available information on genetic variability must be continuously updated. In this study, we assessed the molecular ...
SSR-based assessment of genetic diversity in South American Vitis vinifera varieties
(Elsevier Ireland, 2006-06)
Six SSR loci, previously developed for grapevine, were analyzed to evaluate the genetic variability and cultivar relatedness in a collection of 25 autochthonous Vitis vinifera varieties from Perú and Argentina. The number ...
Highly variable AFLP and S-SAP markers for the identification of "Malbec" and "Syrah" clones
(JKI-Institut für Rebenzüchtung, 2009-07)
The retrotransposon-based sequence-specific amplification polymorphism (S-SAP) and the amplified fragment length polymorphism (AFLP) marker systems were used to assess the clonal variation of 14 ‘Syrah’ and 22 ‘Malbec’ ...
Genetic Diversity in Argentine Andean Potatoes by Means of Functional Markers
(Springer, 2018-06)
Andean Potato is a major crop for farmers in the Andes and represents an important gene pool for potato improvement. We present the population structure and genetic diversity of 88 Andigena accessions collected in Northwestern ...
Benchmark datasets of immune receptor-epitope structural complexes
(BioMed Central, 2019-10)
Background: The development of accurate epitope prediction tools is important in facilitating disease diagnostics, treatment and vaccine development. The advent of new approaches making use of antibody and TCR sequence ...
Single-Channel Kinetic Analysis for Activation and Desensitization of Homomeric 5-HT3A Receptors
(Cell Press, 2009-09)
The 5-HT3A receptor is a member of the Cys-loop family of ligand-gated ion channels. To perform kinetic analysis, we mutated the 5-HT3A subunit to obtain a high-conductance form so that single-channel currents can be ...