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Influência do FK-506 sobre a expressão de RANKL e OPG na doença periodontal induzida: estudo in vivo e in vitro
(Universidade Estadual Paulista (Unesp), 2014)
NF-kappa B as a therapeutic target in inflammatory-associated bone diseases
(Elsevier, 2017)
Inflammation is a defensive mechanism for pathogen clearance and maintaining tissue homeostasis. In the skeletal system, inflammation is closely associated with many bone disorders including fractures, nonunions, periprosthetic ...
Heme Oxygenase-1 (HO-1) Expression in Prostate Cancer Cells Modulates the Oxidative Response in Bone Cells.
(Public Library Science, 2013-11-04)
Prostate cancer (PCa) is a leading cause of death among males. It is currently estimated that inflammatory responses are linked to 15-20% of all deaths from cancer worldwide. PCa is dominated by complications arising from ...
Rol de Hemo oxigenasa 1 (HO-1) en la progresión ósea del cáncer de próstata
(2019-03-22)
El cáncer de próstata (CaP) es el segundo tipo de cáncer másfrecuentemente diagnosticado en hombres. En estadíos avanzados laenfermedad puede diseminarse siendo el hueso el principal sitio de metástasis.Este no es un evento ...
Brucella abortus invasion of osteocytes modulates connexin 43 and integrin expression and induces osteoclastogenesis via receptor activator of NF-κB ligand and tumor necrosis factor alpha secretion
(American Society for Microbiology, 2015-11)
Osteoarticular brucellosis is the most common localization of human active disease. Osteocytes are the most abundant cells of bone. They secrete factors that regulate the differentiation of both osteoblasts and osteoclasts ...
IL-22-expressing CD4(+)AhR(+) T lymphocytes are associated with RANKL-mediated alveolar bone resorption during experimental periodontitis
(WILEY, 2019)
Background and Objective Over the past few years, the importance of interleukin-22 (IL-22) and T-helper (Th)22 lymphocytes in the pathogenesis of periodontitis has become apparent; however, there are still aspects that are ...
IL-22-expressing CD4(+)AhR(+) T lymphocytes are associated with RANKL-mediated alveolar bone resorption during experimental periodontitis
(Blackwell Munksgaard, 2019-10)
Background and Objective Over the past few years, the importance of interleukin-22 (IL-22) and T-helper (Th)22 lymphocytes in the pathogenesis of periodontitis has become apparent; however, there are still aspects that are ...