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Instantaneous Interactions Between Nanoparticles and Tumors Dictated by Bayes Theorem
(IEEE, 2023)
This paper focuses on the process of internalization for nanoparticles that have been sent as part of a scheme of targeted drug delivery. In this manner, it is applied in a straightforward manner the Bayes’s theorem since ...
A multilayer network approach for guiding drug repositioning in neglected diseases
(Public Library of Science, 2016-01)
Drug development for neglected diseases has been historically hampered due to lack of market incentives. The advent of public domain resources containing chemical information from high throughput screenings is changing the ...
Proteomic and Bioinformatic Analysis of Trypanosoma cruzi Chemotherapy and Potential Drug Targets: New Pieces for an Old Puzzle
(Bentham Science Publishers, 2015)
Neuroprotection in hypoxic-ischemic brain injury targeting glial cells
(Bentham Science Publishers B.V., 2017)
Glycoprotein Ib/IX complex is the target in rifampicin-induced immune thrombocytopenia
(BLACKWELL SCIENCE LTD, 2000)
Thrombocytopenia is a major adverse effect of several drug treatments. Rifampicin has been recognized as a cause of immune thrombocytopenia during intermittent high-dose therapy. We characterized the antibody of a patient ...
Folate biosynthesis pathway: mechanisms and insights into drug design for infectious diseases
(Future Sci Ltd, 2018-04-01)
Folate pathway is a key target for the development of new drugs against infectious diseases since the discovery of sulfa drugs and trimethoprim. The knowledge about this pathway has increased in the last years and the ...
Immunoliposomes: A review on functionalization strategies and targets for drug delivery
(2017-11-01)
Nanoparticles, especially liposomes, have gained prominence in the field of drug delivery for the treatment of human diseases, particularly cancer; they provide several advantages, including controlled drug release, ...
Current advances in antitubercular drug discovery: potent prototypes and new targets
(Bentham Science Publishers, 2015)
Therapeutic targets in chagas disease
(2017-01-01)
Optimal pharmacotherapy occurs when we have selectivity and no toxicity. The discovery of specific pathways or enzymes that are vital forcell or parasite survival is also vital for the design of new specific, non-toxic ...
Shikimate kinase: A potential target for development of novel antitubercular agents
(Bentham Science Publ Ltd, 2014)