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Cross-talk with β2-adrenoceptors enhances ligand affinity properties from endothelial alpha1D-adrenoceptors that mediates carotid relaxation
(2013-09-01)
Objectives Our main objectives were to investigate the affinity properties of endothelial and muscular α1D-adrenoceptors and to characterize the cross-talk between endothelial α1D- adrenoceptors and β2-adrenoceptors in rat ...
Cross-talk with β2-adrenoceptors enhances ligand affinity properties from endothelial alpha1D-adrenoceptors that mediates carotid relaxation
(2013-09-01)
Objectives Our main objectives were to investigate the affinity properties of endothelial and muscular α1D-adrenoceptors and to characterize the cross-talk between endothelial α1D- adrenoceptors and β2-adrenoceptors in rat ...
Cellular mechanisms against ischemia reperfusion injury induced by the use of anesthetic pharmacological agents
(Elsevier, 2014)
Ischemia–reperfusion (IR) cycle in the myocardium is associated with activation of an injurious cascade,
thus leading to new myocardial challenges, which account for up to 50% of infarct size. Some evidence
implicates ...
Pharmacological models and approaches for pathophysiological conditions associated with hypoxia and oxidative stress
(Pergamon-Elsevier, 2016)
Hypoxia is the failure of oxygenation at the tissue level,where the reduced oxygen delivered is not enough to satisfy
tissue demands. Metabolic depression is the physiological adaptation associated with reduced oxygen ...
Is the renal (Na + K)-ATPase modulated by intracellular messengers?
(1992)
The basic cellular mechanisms involved in the regulation of (Na + K)-ATPase are discussed. Various ligands seem to be responsible for the short-term modulation of this enzyme activity (intracellular messengers). Cytosolic ...
Cardiac fibroblasts as sentinel cells in cardiac tissue: Receptors, signaling pathways and cellular functions
(Elsevier, 2015)
Cardiac fibroblasts (CF) not only modulate extracellular matrix (ECM) proteins homeostasis, but also respond to chemical and mechanical signals. CF express a variety of receptors through which they modulate the proliferation/cell ...
Highlights in endocytosis of nanostructured systems
(2017-06-01)
The focus of this review is the cellular internalisation mechanism of nanostructured systems (NSs) and their endosomal escape for targeted drug delivery. Endocytosis is a cellular process of internalisation of different ...
Chrysin modulates genes related to inflammation, tissue remodeling, and cell proliferation in the gastric ulcer healing
(2020-02-01)
Chrysin exhibits anti-inflammatory and antioxidant activities. Here, the gastroprotective effect of chrysin was investigated in mouse models of gastric ulcer induced by absolute ethanol, acetic acid, and ischemia-reperfusion ...
Effect Of Mk-801 And Clozapine On The Proteome Of Cultured Human Oligodendrocytes
(FRONTIERS MEDIA SALAUSANNE, 2016)