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Successful production of the potato antimicrobial peptide Snakin-1 in baculovirus-infected insect cells and development of specific antibodies
(2017)
Background: Snakin-1 (StSN1) is a broad-spectrum antimicrobial cysteine-rich peptide isolated from Solanum tuberosum. Its biotechnological potential has been already recognized since it exhibits in vivo antifungal and ...
Resistance of melanized yeast cells of Paracoccidioides brasiliensis to antimicrobial oxidants and inhibition of phagocytosis using carbohydrates and monoclonal antibody to CD18
(Instituto Oswaldo Cruz, Ministério da Saúde, 2009-07-01)
Paracoccidioides brasiliensis, a thermal dimorphic fungal pathogen, produces a melanin-like pigment in vitro and in vivo. We investigated the involvement of carbohydrates and monoclonal antibody to CD18, on phagocytosis ...
The multitude of targets for the immune system and drug therapy in the fungal cell wall
(Elsevier B.V., 2005-04-01)
Recent studies on fungi revealed that several cytosolic and membrane components migrate to the cell wall together with secreted proteins and biosynthetic polysaccharides to build a dynamic immunoreactive structure. New ...
Antibody mediated osseous regeneration: A new strategy for bioengineering
(2020-01-01)
This chapter provides a brief review of bone biology and metabolism, focusing on the regenerative potential of bone tissues. In this context, we discussed the main clinical approaches to enhance bone regeneration, concentrating ...
Successful production of the potato antimicrobial peptide Snakin-1 in baculovirus-infected insect cells and development of specific antibodies
(BioMed Central, 2017-11)
Background: Snakin-1 (StSN1) is a broad-spectrum antimicrobial cysteine-rich peptide isolated from Solanumtuberosum. Its biotechnological potential has been already recognized since it exhibits in vivo antifungal ...
New complementary and alternative therapies to control methicillinresistant staphylococcus aureus (MRSA) infection
(2020-01-01)
Methicillin-Resistant Staphylococcus aureus (MRSA) became a major public health concern worldwide. The increase in the prevalence of antibiotic resistant pathogens, the limited efficacy and the adverse events associated ...
The antimicrobial peptide MK58911-NH2 acts on planktonic, biofilm, and intramacrophage cells of cryptococcus neoformans
(2021-12-01)
Cryptococcosis is associated with high rates of morbidity and mortality, especially in AIDS patients. Its treatment is carried out by combining amphotericin B and azoles or flucytosine, which causes unavoidable toxicity ...
Limited diagnostic usefulness of antibodies to cytoplasmic proteins of Brucella in early-treated human brucellosis.
(Taylor & Francis As, 2001-12)
Antibodies to cytoplasmic proteins (CP) of Brucella have been shown to be useful for the diagnosis of human brucellosis; however, some early-diagnosed patients lack such an antibody response while having high titers of ...