Buscar
Mostrando ítems 1-10 de 73
PI3K/AKT pathway is altered in the endometriosis patient’s endometrium and presents differences according to severity stage
(Informa Healthcare, 2019-10)
Based on the inflammatory nature and hormone-dependency of endometriosis, PI3K/AKT signaling appears to influence its progression. Could the endometriosis stages be linked to differential changes in PI3K/AKT pathway ...
Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer
(Biomed Central Ltd., 2015)
BACKGROUND:
PTEN is a tumor suppressor gene that regulates the PTEN/PI3k/AKT/mTOR pathway, which is frequently altered in human cancers including gallbladder cancer (GBC). To determine the frequency of PTEN expression in ...
Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer
(Biomed Central Ltd., 2015)
BACKGROUND:
PTEN is a tumor suppressor gene that regulates the PTEN/PI3k/AKT/mTOR pathway, which is frequently altered in human cancers including gallbladder cancer (GBC). To determine the frequency of PTEN expression in ...
Down-regulation of Hsp27 (HSPB1) in MCF-7 human breast cancer cells induces up-regulation of PTEN.
(Springer, 2013-03)
Hsp27 (HSPB1) is usually overexpressed in breast cancers affecting the disease outcome and the sensitivity of tumors to chemotherapy and radiotherapy. Hsp27 interacts with other proteins such as β-catenin, histone deacetylase ...
Genetic-molecular study of the EGFR/PI3K/AKT pathway in high and low grade gliomas
Gliomas account for 70% of all central nervous system (CNS) tumors and are classified according to the WHO in low (I and II) or high (III and IV or glioblastoma multiforme, GBM) grade malignancies. The survival of patients ...
Genetic-molecular study of the egfr/ pi3k/akt pathway in high and low grade gliomas
Gliomas account for 70% of all central nervous system (CNS) tumors and are classified according to the WHO in low (I and II) or high (III and IV or glioblastoma multiforme, GBM) grade malignancies. The survival of patients ...
Análise da expressão da proteína PTEN em carcinoma papilar de tireoide
(Universidade Federal de Minas GeraisUFMG, 2012-08-03)
PTEN (phosphatase and tensin homologue) is a tumor suppressor gene, located on chromosome 10q23.3. The gene negatively regulates the PI3K/Akt pathway, stimulating apoptosis and blocking the cell proliferation and cell ...