Buscar
Mostrando ítems 1-10 de 91
Antifungal and anti-biofilm activity of designed derivatives from kyotorphin
(Elsevier B.V., 2020-05-01)
Kyotorphin (KTP, L-tyrosyl-L-arginine) is an endogenous analgesic neuropeptide first isolated from bovine brain in 1979. Previous studies have shown that kyotorphins possess anti-inflammatory and antimicrobial activity. ...
Regulation of stress-induced reduced myelopoiesis in rats
(Pergamon-elsevier Science LtdOxfordInglaterra, 1997)
Design of inhibitors for human tissue kallikrein using non-natural aromatic and basic amino acids
(Walter de Gruyter & Co, 2002-05-01)
We explored the unique substrate specificity of the primary S1 subsite of human urinary kallikrein (hK1), which accepts both Phe or Arg synthesizing and assaying peptides derived from PhenylacetylPheSer ArgEDDnp, a previously ...
Antinociceptive and anti-inflammatory effects of novel dietary protein hydrolysate produced from whey by proteases of Cynara cardunculus
(Elsevier Sci LtdOxfordInglaterra, 2013)
Where spiders and cone snails meet: development of novel sodium channel probes
(Universidade Federal de Minas GeraisUFMG, 2019-03-21)
Voltage-gated sodium (NaV) channels play crucial roles in a range of (patho)physiological processes. Much interest has arisen within the pharmaceutical industry to pursue these channels as analgesic targets following the ...
Bioprospecção de compostos bioativos: descoberta de peptídeos inovadores presentes na fauna acompanhante
(Universidade Estadual Paulista (Unesp), 2022-02-21)
A fauna acompanhante está presente nas atividades pesqueiras realizadas por meio da rede de arrasto e na maioria dos casos, somam cerca de 50% da captura. Por não representar valor econômico, esta é comumente descartada ...
Physiology and Therapeutic Potential of the Thymic Peptide Thymulin
(Bentham Science Publishers, 2014-07)
Thymulin is a thymic hormone exclusively produced by the epithelial cells of the thymus. After its discovery and initial characterization in the ‘70s, it was demonstrated that the production and secretion of thymulin are ...