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Toxicological interactions in insects exposed to simple mixtures containing botanical monoterpenes and conventional insecticides
(Juniper Publishers, 2020-11)
Due to its low toxicity in mammals and very low environmental impact, some botanical monoterpenes with insecticidal activity are an attractive alternative to conventional insecticides. There is extensive literature on the ...
The metabolic and toxicological considerations for immunosuppressive drugs used during pancreas transplantation
(Informa Healthcare, 2012-12-01)
Introduction: Pancreas-kidney transplant is an effective treatment for patients with insulin-dependent dabetes and chronic renal failure. Reduction in technical failure loss and early acute rejection rates contributed to ...
2,2'azo-bis-amidinopropane as a radical source for lipid peroxidation and enzyme inactivation studies
(Informa Healthcare, 1991)
1. 2,2'Azo-bis-amidinopropane (ABAP) thermal decomposition produces free radicals that initiate the lipid peroxidation of erythrocyte ghost membranes. 2. Addition of 6-n-propyl-2-thiouracil decreases the rate of the process, ...
Chloroquine to fight COVID-19: A consideration of mechanisms and adverse effects?
The COVID-19 outbreak emerged in December 2019 and has rapidly become a global pandemic. A great deal of
effort has been made to find effective drugs against this disease. Chloroquine (CQ) and hydroxychloroquine
(HCQ) ...
Drug-acetaldehyde interactions during ethanol metabolism in vitro
(Oxford University Press, 1991)
Acetaldehyde, at concentrations occurring in vivo was found to avidly react in vitro with several clinically relevant drugs. The greatest reactivity was observed for the hydrazine and hydrazide-containing drugs, hydralazine ...
Interaction between humic substances and metallic ions: A selectivity study of humic substances and their possible therapeutic application
(2007-09-06)
The complexation capacity of humic substances extracted from peat samples taken from the Mogi River in Ribeirao Preto, SP, Brazil, was determined using metal ions (Al(III), Pb(II), Cr(VI) and Cd(II)), yielding the following ...
Interaction between humic substances and metallic ions: A selectivity study of humic substances and their possible therapeutic application
(2007-09-06)
The complexation capacity of humic substances extracted from peat samples taken from the Mogi River in Ribeirao Preto, SP, Brazil, was determined using metal ions (Al(III), Pb(II), Cr(VI) and Cd(II)), yielding the following ...
Identification of Sudan III-(deoxy)-guanosine adducts formed in situ in a reaction with no catalyst
(Taylor & Francis Ltd, 2013-10-01)
Incubation of guanosine and Sudan III induces the formation of a stable adduct, which may be identified using a spectrophotometric technique and mass spectroscopy. The high nucleophilicity of the C-8 position and its ...
Challenges on the toxicological predictions of engineered nanoparticles
(2017-10-01)
The perceived enormous potential of nanotechnology in contributing to sustainable innovation has led to the growth of investments into new industrial applications and consumer products. However, the lack of tools that are ...