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The Insuline AnaloguesAnálogos de Insulina
(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana, 2001)
Randomized double-blind clinical study in patients with COVID-19 to evaluate the safety and efficacy of a phytomedicine (P2Et)
(Frontiers Media S.AInmunovirologíaLausanne, Suiza, 2023)
Venom alkaloids against Chagas disease parasite: search for effective therapies
(Nature Research, 2020-06)
Chagas disease is an important disease affecting millions of patients in the New World and is caused by a protozoan transmitted by haematophagous kissing bugs. It can be treated with drugs during the early acute phase; ...
Influence on effectiveness of early treatment with anti-TNF therapy in rheumatoid arthritis
(Canadian Society for Pharmaceutical Sciences, 2012-05-16)
Purpose. To evaluate the association between starting early treatment with anti-TNF and effectiveness as well as the possibility of applying therapeutic spacing in daily practice in patients with rheumatoid arthritis (RA). ...
V1b Receptor Antagonist SSR149415 and Naltrexone Synergistically Decrease Excessive Alcohol Drinking in Male and Female Mice
(Wiley Blackwell Publishing, Inc, 2018-01)
Background: A recent clinical trial found that pharmacological blockade of V1b receptors reduces alcohol relapse in alcohol-dependent patients. SSR149415 is a selective V1b receptor antagonist that has potential for ...
RUNX2 overexpression generates endocrine resistance in human luminal breast cancer xenografts
(Fundación Revista Medicina, 2021)
T47D and IBH6 cells that overexpress RUNX2 show high levels of FGFR2 and FGF2, supporting the hypothesis that FGF2 increases RUNX2 and, in turn, RUNX2 increases FGF2, maintaining a positive loop. However, in these models ...
Levels of Bone Turnover in Saliva Correlated with Antirresortive Treatment: Experimental Study
(Austin Publishing Group, 2020-12)
Background: Bone turnover markers are useful to evaluate bone loss and monitor anticatabolic treatments in a short period. The effectiveness of saliva to reflect changes in bone turnover markers during the early administration ...
In vitro and in vivo activity of voriconazole and benznidazole combination on trypanosoma cruzi infection models
(Elsevier Science, 2020-11)
Combination therapy has been proposed as an ideal strategy to reduce drug toxicity and improve treatment efficacy in Chagas disease. Previously, we demonstrated potent in vivo anti-Trypanosoma cruzi activity of voriconazole. ...