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Clinical research in Latin America and Argentina: time for a change?Investigación clínica en América Latina y Argentina: ¿es tiempo de cambios?
(Universidad Nacional de Lanús, 2011)
Drug delivery vehicles on a nano-engineering perspective
(Elsevier, 2014-04)
Nanoengineered drug delivery systems (nDDS) have been successfully used as clinical tools for not only modulation of pharmacological drug release profile but also specific targeting of diseased tissues. Until now, encapsulation ...
Quantum chemical approaches in structure-based virtual screening and lead optimization
(Frontiers Research Foundation, 2018-05)
Today computational chemistry is a consolidated tool in drug lead discovery endeavors. Due to methodological developments and to the enormous advance in computer hardware, methods based on quantum mechanics (QM) have gained ...
Cys-loop receptors in Caenorhabditis elegans as pharmacological drug targets (Simposio)
(Fundación Revista Medicina, 2019)
The free-living nematode Caenorhabditis elegans has emerged as a powerful model for the study of the nervous system and human diseases and as a model for antiparasitic drug discovery. This nematode has also shown promise ...
A new method for 3D printing drugs: Melting solidification printing process
(Future Medicine, 2020-09)
Conventional manufacturing methods for oral administration forms are adapted to produce large batches of tablets of identical dosage form (same geometry, size and dosage). These methods are inflexible or not economically ...
Nanotechnology and Drug Delivery
(Springer, 2018)
Nowadays nanotechnology represents an expanding field that is providing powerfultools for the pharmaceutical industry such as polymeric, solid lipid, metallic, and magnetic NPs, liposomes, dendrimers, and other nanostructures. ...
Chagas disease treatment: From new therapeutic targets to drug discovery and repositioning
(Bentham Science Publishers, 2019-12)
Chagas disease, caused by the protozoan Trypanosoma cruzi, currently affects millions of people worldwide although it is only endemic in America. Chagas is considered a neglected tropical disease because it afflicts the ...
Nanostructured voltammetric sensor for ultra-trace anabolic drug determination in food safety field
(2013-11)
A sensitive electrochemical sensor for clenbuterol (CL) determination in bovine urine samples was designed. This drug was originally developed for the treatment of respiratory pathologies. However, in the livestock industry, ...