Buscar
Mostrando ítems 51-60 de 1718
MERTK as negative regulator of human T cell activation
(Federation of American Societies for Experimental Biology, 2015-04)
The aim of this study was to test the hypothesis whether MERTK, which is up-regulated in human DCs treated with immunosuppressive agents, is directly involved in modulating T cell activation. MERTK is a member of the TAM ...
Self-assembled phosphate-polyamine networks as biocompatible supramolecular platforms to modulate cell adhesion
(Royal Society of Chemistry, 2018-08)
The modulation of cell adhesion via biologically inspired materials plays a key role in the development of realistic platforms to envisage not only mechanistic descriptions of many physiological and pathological processes ...
Understanding new molecular and cell biology findings based on progressive scientific practices and interconnected activities in undergraduate students
(John Wiley & Sons Inc, 2021-03)
Nowadays Molecular Cell Biology (MCB) must be taught as science is practiced. Even though there are several approaches based on scientific practices, a key aspect is to define the purpose of each of these teaching strategies ...
Synthetic lactulose amines: novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectin-mediated homotypic cell aggregation and endothelial cell morphogenesis
(Oxford Univ Press Inc, 2006-03)
Galectins, a family of structurally related carbohydrate-binding proteins, contribute to different events associated with cancer biology, including apoptosis, homotypic cell aggregation, angiogenesis and tumor-immune escape. ...
Donors define whether CD19+CD27+ tonsillar B cells are mostly memory or germinal-center B cells
(Nature Publishing Group, 2015-05)
CD27 has been used by numerous indepen- dent groups as a pan-memory B-cell marker not only for the identification of peripheral blood (PB) memory B cells (Bmem) but also for spleen Bmem, tonsillar Bmem and bone marrow Bmem. ...
Leptin promotes cell proliferation and survival of trophoblastic cells
(Society for the Study of Reproduction, 2007-02)
Leptin, the 16-kDa protein product of the obese gene, was originally considered as an adipocyte-derived signaling molecule for the central control of metabolism. However, leptin has been suggested to be involved in other ...
Linoleic and oleic acids enhance cell migration by altering the dynamics of microtubules and the remodeling of the actin cytoskeleton at the leading edge
(Nature Publishing Group, 2021-12)
Fatty acids (FA) have a multitude of biological actions on living cells. A target of their action is cell motility, a process of critical importance during cancer cell dissemination. Here, we studied the effect of unsaturated ...
Numerical simulation of a multiscale cell motility model based on the kinetic theory of active particles
(MDPI, 2019-08-03)
In this work, we deal with a kinetic model of cell movement that takes into consideration the structure of the extracellular matrix, considering cell membrane reactions, haptotaxis, and chemotaxis, which plays a key role ...
Cementoin-SLPI fusion protein binds to human monocytes and epithelial cells and shows higher biological activity than SLPI
(Nature Publishing Group, 2018-12)
Secretory Leukocyte Proteinase Inhibitor (SLPI) is an antiinflammatory peptide that blocks the activity of serine proteases, primarily the neutrophil elastase. In an attempt to direct the activity of SLPI on inflamed sites, ...
When cells lose water: Lessons from biophysics and molecular biology
(Elsevier, 2008-10)
Organisms living in deserts and anhydrobiotic species are useful models for unraveling mechanisms used to overcome water loss. In this context, late embryogenesis abundant (LEA) proteins and sugars have been extensively ...