Artículos de revistas
Brain spect in alcohol, cocaine and MDMA
International Journal of Neuropsychopharmacology
Objective: The aim of this paper is to try to corroborate a diagnostic marker in alcohol and substance abuse through brain imaging using Brain Spect, based on the pioneering work in psychiatry by Andreasen in 1988 in relation to schizophrenia, Zohar in 1989 in relation to OCD, Lesser and Mena in 1990 in depressive disorder and of the authors in 2010. Methods: This paper is a simple, random revision of patients seen at the Neuropsychiatric Diagnostic Center of Ricardo Palma Clinic in Lima between 2009–2015 (7 years). The patients had to have the only diagnosis of: Dependence to cocaine, M D M A (3, 4 - Methylenedioxymethaphetamin), or alcohol. All of them were given a Single Photon Emission Computer Tomography (SPECT) and as a radioisotope was used Tecnesium and as the tracer Neurolite with all requirements of the case, we studied 50 patients with Cocaine, 50 with MDMA and 50 with alcoholism. These patients were compared with 50 of healthy Controls that we have on our database because we have an experience of 20 years. Results: The results for cocaine were fronto parieto temporal multifocal hypo and hyperperfusion, for MDMA a hypoperfusion of the left cortical hemisphere and for alcoholism a hypoperfusion of middle cingulated and ventral fronto-parietal cortex. We discuss our findings and are treated to give a clinical-imaginological interpretation. Conclusions: The results confirm that the findings serve as diagnostic markers in the dependencies to alcohol, MDMA and cocaine in 2010andy 2016.