dc.creator | Romero P, Carlos | |
dc.creator | Morales R, Mónica | |
dc.creator | Donaire R, Luisa | |
dc.creator | Llanos, Osvaldo | |
dc.creator | Cornejo R, Rodrigo | |
dc.creator | Gálvez A, Ricardo | |
dc.creator | Castro O, José | |
dc.date.accessioned | 2019-03-11T12:56:02Z | |
dc.date.available | 2019-03-11T12:56:02Z | |
dc.date.created | 2019-03-11T12:56:02Z | |
dc.date.issued | 2008 | |
dc.identifier | Revista Medica de Chile, Volumen 136, Issue 1, 2018, Pages 88-92 | |
dc.identifier | 00349887 | |
dc.identifier | 07176163 | |
dc.identifier | https://repositorio.uchile.cl/handle/2250/164586 | |
dc.description.abstract | Propofol infusion syndrome (PRIS) is a rare but potentially lethal complications. This disorder is triggered under unknown circumstances by a propofol infusion of more than 5 mg/kg/h for more than 48 h. PRIS is characterized by a multiorgan failure and rhabdomyolysis and is induced by a disturbance in mitochondrial long chain fatty acid oxidation. We report a 43 year-old woman who underwent brain surgery due to a vascular malformation. In the immediate postoperative period, she had an unexplained and severe lactic acidosis. During anaesthesia, she received a propofol infusion of 7 mg/kg/h that continued in the UCI at a rate of 3.5 mg/kg/h, for 8 hours more. The suspicion of PRIS motivated immediate discontinuation of propofol with rapid correction of lactic acidosis and full recovery of the patient. | |
dc.language | en | |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
dc.source | Revista Medica de Chile | |
dc.subject | Acidosis, lactic | |
dc.subject | Propofol | |
dc.subject | Rhabdomyolysis | |
dc.title | Severe lactic acidosis caused by propofol infusion. Report of one case Acidosis láctica severa asociada a infusión de propofol. Caso clínico | |
dc.type | Artículo de revista | |