Artículos de revistas
Intestinal paracellular absorption is necessary to support the sugar oxidation cascade in nectarivorous bats
Fecha
2016-03Registro en:
Rodriguez Peña, Nelly; Price, Edwin R.; Caviedes Vidal, Enrique Juan Raul; Flores Ortiz, Cesar M.; Karasov, William H.; Intestinal paracellular absorption is necessary to support the sugar oxidation cascade in nectarivorous bats; Company of Biologists; Journal of Experimental Biology; 219; 6; 3-2016; 779-782
0022-0949
CONICET Digital
CONICET
Autor
Rodriguez Peña, Nelly
Price, Edwin R.
Caviedes Vidal, Enrique Juan Raul
Flores Ortiz, Cesar M.
Karasov, William H.
Resumen
We made the first measurements of the capacity for paracellular nutrient absorption in intact nectarivorous bats. Leptonycteris yerbabuenae (20 g mass) were injected with or fed inert carbohydrate probes L-rhamnose and D(+)-cellobiose, which are absorbed exclusively by the paracellular route, and 3-O-methyl-D-glucose (3OMD-glucose), which is absorbed both paracellularly and transcellularly. Using a standard pharmacokinetic technique, we collected blood samples for 2 h after probe administration. As predicted, fractional absorption (f) of paracellular probes declined with increasing Mr in the order of rhamnose (f=0.71)>cellobiose ( f=0.23). Absorption of 3OMD-glucose was complete (f=0.85; not different from unity). Integrating our data with those for glucose absorption and oxidation in another nectarivorous bat, we conclude that passive paracellular absorption of glucose is extensive in nectarivorous bat species, as in other bats and small birds, and necessary to support high glucose fluxes hypothesized for the sugar oxidation cascade.