Artículos de revistas
Disruption of lipid rafts enhances the effect of lactobacilli on the production of tumor necrosis factor-alpha in mononuclear blood cells
Fecha
2008-12-07Registro en:
Soria, Mario Alberto; Mechoud, Monica Adriana; Martin de Quevedo, Angela; Font, Graciela Maria; Rodriguez, Ana Virginia; Disruption of lipid rafts enhances the effect of lactobacilli on the production of tumor necrosis factor-alpha in mononuclear blood cells; Japan Soc Biosci Biotechn Agrochem; Bioscience, Biotechnology and Biochemistry; 72; 12; 7-12-2008; 3293-3296
0916-8451
1347-6947
CONICET Digital
CONICET
Autor
Soria, Mario Alberto
Mechoud, Monica Adriana
Martin de Quevedo, Angela
Font, Graciela Maria
Rodriguez, Ana Virginia
Resumen
We investigated, to determine whether disruption of lipid rafts would influence the effect of three selected strains of Lactobacillus on TNF-alpha production by peripheral blood mononuclear cells. Two strains increased TNF-alpha production; and the third one reduced cytokine levels. Disruption of rafts changed the immunomodulatory effect of the three strains. This is the first report on a potential role of rafts in lactobacilli-cell interaction.