Application of computed tomography images in the evaluation of magnetic nanoparticles biodistribution

dc.creatorDIAS, Argleydson Leao
dc.creatorKUNZEL, R.
dc.creatorLEVENHAGEN, Ronaldo Savarino
dc.creatorOKUNO, Emico
dc.date.accessioned2012-10-20T04:12:14Z
dc.date.accessioned2018-07-04T15:41:02Z
dc.date.available2012-10-20T04:12:14Z
dc.date.available2018-07-04T15:41:02Z
dc.date.created2012-10-20T04:12:14Z
dc.date.issued2010
dc.identifierJOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, v.322, n.16, p.2405-2407, 2010
dc.identifier0304-8853
dc.identifierhttp://producao.usp.br/handle/BDPI/29464
dc.identifier10.1016/j.jmmm.2010.02.046
dc.identifierhttp://dx.doi.org/10.1016/j.jmmm.2010.02.046
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1626104
dc.description.abstractIn this work we evaluate the effectiveness of computed tomography images as a tool to determine magnetic nanoparticle biodistribution over biological tissues. For this purpose, tomography images for magnetic nanoparticles, composed of Fe(3)O(4), coated with 2,3-dimercaptosuccinic acid (DMSA), were generated at several material concentrations. The comparison of CT numbers, calculated from these images generated at clinical conditions, with typical CT numbers for biological tissues, shows that the detection of nanoparticle in most tissues is only possible for high material concentrations. (C) 2010 Elsevier B.V. All rights reserved.
dc.languageeng
dc.publisherELSEVIER SCIENCE BV
dc.relationJournal of Magnetism and Magnetic Materials
dc.rightsCopyright ELSEVIER SCIENCE BV
dc.rightsrestrictedAccess
dc.subjectMagnetic nanoparticle
dc.subjectComputed tomography
dc.subjectImaging contrast
dc.subjectIodine
dc.titleApplication of computed tomography images in the evaluation of magnetic nanoparticles biodistribution
dc.typeArtículos de revistas


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