dc.creator | PESARO, Antonio Eduardo | |
dc.creator | SOEIRO, Alexandre de Matos | |
dc.creator | SERRANO, Carlos Vicente | |
dc.creator | GIRALDEZ, Roberto Rocha | |
dc.creator | LADEIRA, Renata Teixeira | |
dc.creator | NICOLAU, José Carlos | |
dc.date.accessioned | 2012-03-26T18:12:20Z | |
dc.date.accessioned | 2018-07-04T14:09:45Z | |
dc.date.available | 2012-03-26T18:12:20Z | |
dc.date.available | 2018-07-04T14:09:45Z | |
dc.date.created | 2012-03-26T18:12:20Z | |
dc.date.issued | 2010 | |
dc.identifier | Clinics, v.65, n.3, p.265-270, 2010 | |
dc.identifier | 1807-5932 | |
dc.identifier | http://producao.usp.br/handle/BDPI/8544 | |
dc.identifier | 10.1590/S1807-59322010000300005 | |
dc.identifier | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322010000300005 | |
dc.identifier | http://www.scielo.br/pdf/clin/v65n3/a05v65n3.pdf | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1606692 | |
dc.description.abstract | INTRODUCTION: Oral β-blockers improve the prognosis of patients with acute myocardial infarction, while atrial fibrillation worsens the prognosis of this population. The reduction of atrial fibrillation incidence in patients treated with β-blockers could at least in part explain the benefits of this drug. OBJECTIVE: To investigate the effect of β-blockers on the incidence of atrial fibrillation in patients with acute myocardial infarction. METHODS: We analyzed 1401 patients with acute myocardial infarction and evaluated the occurrence or absence of atrial fibrillation, the use of oral β-blockers and mortality during the first 24 hours. RESULTS: a) The use of β-blockers was inversely correlated with the presence of atrial fibrillation (ρ = 0.004; OR = 0.54). b) Correlations with mortality were as follows: 31.5% in patients with atrial fibrillation, 9.2% in those without atrial fibrillation (ρ < 0.001; Odds Ratio = 4.52), and 17.5% in patients not treated with β-blockers and 6.7% in those who received the drug (ρ < 0.001; OR = 0.34). c) Adjusted Models: The presence of atrial fibrillation was independently correlated with mortality (OR = 2.48, ρ = 0.002). The use of β-blockers was inversely and independently correlated with mortality (OR = 0.53; ρ = 0.002). The patients who used β-blockers showed a lower risk of atrial fibrillation (OR = 0.59; ρ = 0.029) in the adjusted model. CONCLUSION: The presence of atrial fibrillation and the absence of oral β-blockers increased in-hospital mortality in patients with acute myocardial infarction. Oral β-blockers reduced the incidence of atrial fibrillation, which might be at least partially responsible for the drug's benefit. | |
dc.language | eng | |
dc.publisher | Faculdade de Medicina / USP | |
dc.relation | Clinics | |
dc.rights | Copyright Faculdade de Medicina / USP | |
dc.rights | openAccess | |
dc.subject | Acute myocardial infarction | |
dc.subject | β-blockers | |
dc.subject | Atrial fibrillation | |
dc.subject | Mortality | |
dc.subject | Arrhythmias | |
dc.title | Effect of β-blockers on the risk of atrial fibrillation in patients with acute myocardial infarction | |
dc.type | Artículos de revistas | |