INFLAMMATORY REACTION OF RAT STRIATED-MUSCLE TO PARTICLES OF CARBON-FIBER-REINFORCED CARBON

dc.creatorBELANGERO, WD
dc.creatorKOBERLE, G
dc.creatorHADLER, WA
dc.date1993
dc.dateAUG
dc.date2014-07-30T14:33:27Z
dc.date2015-11-26T17:47:34Z
dc.date2014-07-30T14:33:27Z
dc.date2015-11-26T17:47:34Z
dc.date.accessioned2018-03-29T00:30:14Z
dc.date.available2018-03-29T00:30:14Z
dc.identifierBrazilian Journal Of Medical And Biological Research. Assoc Bras Divulg Cientifica, v. 26, n. 8, n. 819, n. 826, 1993.
dc.identifier0100-879X
dc.identifierWOS:A1993LV31400004
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/60163
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/60163
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1288820
dc.description1. Carbon fiber reinforced carbon (CFRC) was implanted in rats as particles measuring 30 mum or 11 mum, denoted as CFRC-A and CFRC-B, respectively. Titanium (Ti) and vitreus carbon (VC) were used as controls. Ti was used with the same particle size as CFRC (Ti-A or Ti-B). The VC particles measured 11 mum. All materials were separately sterilized on ethylene oxide before use. 2. One hundred and ten female Wistar rats, weighing 180 to 220 g, were divided into six groups of 4 to 5 animals each, according the time of the observation (1, 2, 4, 8, 16 and 52 weeks). 3. Under aseptic conditions, one 3-0 curette full of CFRC-A or CFRC-B was implanted into the right triceps surae muscle in each animal and the same quantity of Ti-A (paired with CFRC-A) or Ti-B or VC (paired with CFRC-B) was implanted into the left muscle. 4. Histological analysis did not show necrosis of muscular tissue nor exudative reaction during the acute phase. 5. During the chronic phase the particles induced a chronic inflammatory infiltration containing fibroblasts, macrophages and giant cells. VC and CFRC-B induced the lowest inflammatory infiltration and CFRC-A induced the highest one. 6. We suggest that the longer carbon fiber fragments contained in CFRC-A may be responsible for this more intensive reaction, which may restrict the medical use of the preparation.
dc.description26
dc.description8
dc.description819
dc.description826
dc.languageen
dc.publisherAssoc Bras Divulg Cientifica
dc.publisherSao Paulo
dc.publisherBrasil
dc.relationBrazilian Journal Of Medical And Biological Research
dc.relationBrazilian J. Med. Biol. Res.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectCARBON FIBER REINFORCED CARBON
dc.subjectBIOCOMPATIBILITY
dc.subjectSTRIATED MUSCLE
dc.subjectTendon
dc.subjectInduction
dc.subjectImplants
dc.subjectRepair
dc.subjectTerm
dc.titleINFLAMMATORY REACTION OF RAT STRIATED-MUSCLE TO PARTICLES OF CARBON-FIBER-REINFORCED CARBON
dc.typeArtículos de revistas


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