Artículos de revistas
Polypropylene Hollow Fiber Oxygenators: Effect Of The Sorption Of Perfluoropolyethers
Registro en:
Artificial Organs. , v. 24, n. 3, p. 168 - 173, 2000.
0160564X
10.1046/j.1525-1594.2000.06539.x
2-s2.0-0033946491
Autor
Cassiola F.
Kiyohara P.K.
Joekes I.
Institución
Resumen
The introduction of microporous polypropylene hollow fibers in recent years has brought considerable advances to blood oxygenators. However, lifetime and assembly problems are still unresolved. In this work we tried to rate the oxygen permeation velocity by turning the fibers more hydrophobic through the sorption of a perfluorocarbon. Fomblin HC/25, a perfluoropolyether, is well known for its low surface tension and high affinity for oxygen. Celgard X10, X20, and X30 commercial hollow fibers were tested. The hollow fibers showed high affinity for the perfluoropolyether; swelling was clearly shown. A new system for the measurement of oxygen permeation velocity was developed. The oxygen transport velocity was not significantly changed after sorption. The Celgard microporous hollow fibers impregnated with perfluoropolyether showed no water permeation after 2 months of use, reducing one of the most serious problems in the lifetime of these types of fibers. 24 3 168 173 Voorhees, M.E., Oxygenator technology: The future (1994) Perfusion, 9, pp. 229-232 Montoya, J.P., Shanley, C.J., Merz, S.I., Bartlett, R.H., Plasma leakage through microporous membranes: Role of phospholipids (1992) Asaio J, 38, pp. M399-405 Cheng, B.T., Leonard, E.F., Light microscopic visualization of plasma intrusion into microporous hollow fiber (1995) ASAIO J, 41, pp. 863-872 Lund, L.W., Federspiel, W.J., Hattler, B.G., Gas permeability of hollow fiber membranes in a gas-liquid system (1996) J Membrane Science, 117, pp. 207-219 Gaylor, J.D.S., Membrane oxygenators: Influence of design on performance (1994) Perfusion, 9, pp. 173-180 Qi, Z., Microporous hollow fibers for gas absorption: II. Mass transfer across the membrane (1985) J Membrane Science, 23, pp. 333-345 Costello, M.J., Fane, A.G., Hogan, P.A., Schofield, R.W., The effect of shell side hydrodynamics on the performance of axial flow hollow fiber modules (1993) J Membrane Science, 80, pp. 1-11 Wickramasinghe, S.R., Semmens, M.J., Cussler, E.L., Mass transfer in various hollow fiber geometries (1992) J Membrane Science, 69, pp. 235-250 Yasuda, H., Lamaze, C.F., Transfer of gas to dissolved oxygen in water via porous and nonporous polymer membrane J Appl Poly Science, 16, pp. 595-601. , 1072 Kamo, J., Uchida, M., Hirai, T., Yasida, H., Kanada, K., Takemura, T., A new multilayered composite hollow fiber membrane for artificial lung (1990) Artif Organs, 14 (5), pp. 369-372 Yamanouchi, K., Heldebrant, C., Perfluorochemicals as a blood substitute (1992) Chemtech, JUNE, pp. 354-359 Rüdiger, S., Methods for forecasting the usefulness of perfluorocarbons for blood substitutes (1989) J Fluorine Chemistry, 42, pp. 403-412 Lawson, D.D., Moacanin, J., Scherer, K.V., Terranova T.F., Jr., Inghan, J.D., Methods for the estimation of vapor pressures and oxygen solubilities of fluorochemicals for possible application in artificial blood formulations (1978) J Fluorine Chemistry, 12, pp. 221-236 Pantini, G., Moretti, L., Il Fomblin, H.C., Tecnologie chemiche (1988) Ano, 8, pp. 44-48. , 3, Marzo