Artículos de revistas
Differences In Mortality Profile Of Tuberculosis Patients Related To Tuberculosis-aids Co-morbidity [perfil De Mortalidade De Pacientes Com Tuberculose Relacionada à Comorbidade Tuberculose-aids]
Registro en:
Revista De Saude Publica. , v. 38, n. 4, p. 503 - 510, 2004.
348910
2-s2.0-4544325798
Autor
Bosco de Oliveira H.
Marin-Leon L.
Correa Cardoso J.
Institución
Resumen
Objective. To analyze the profile of deaths among tuberculosis patients in Campinas, Brazil, between 1993 and 2000, describing TB-AIDS co-infection and the underlying cause of death in the annual cohorts grouped in two periods 1993-1996 and 1997-2000. Methods. A descriptive study of deaths was conducted among patients in Campinas, Brazil, who were being treated for tuberculosis and those reported as having TB after death. Data from the local Tuberculosis Registry and the Mortality Registry were used. Statistical analyses were performed using Epi Info version 6. Deaths were grouped in two periods (1993-1996 and 1997-2000) and then compared. Results. Of a total of 4,680 patients, there were 737 deaths. The fatality rate was 18.1% in the period 1993-1996 and 13.5% in 1997-2000. After death reporting for patients without treatment was seen in 78 deaths (10.6%). In both periods, there was a prevalence of male deaths (71.3%). TB-AIDS co-infection was found in 55% of deaths and their median age was 30-39 years while the median age was 50-59 years in those without AIDS. Those who were never treated for tuberculosis corresponded to 81.9%. Conclusions. The most important finding was the significant reduction of deaths from 1997 onward that can be related to the introduction of AIDS antiretroviral therapy (HAART). 38 4 503 510 Antunes, J.L.F., Waldman, E.A., Tuberculosis in the twentieth century: Time-series mortality in São Paulo, Brazil, 1900-97 (1999) Cad Saúde Pública, 15, pp. 463-476 Barr, R.G., Diez-Roux, A.V., Knirsch, C.A., Neighborhood poverty and the resurgence of tuberculosis in New York City, 1984-1992 (2001) Am. J. Public Health, 91, pp. 1487-1493 Boerma, J.T., Nunn, A.J., Whitworth, J.A., Mortality impact of the AIDS epidemic: Evidence from community studies in less developed countries (1998) AIDS, 12 (SUPPL. 1), pp. S3-S14 Braun, M.M., Cote, T.R., Rabkin, C.S., Trends in death with tuberculosis during AIDS era (1993) JAMA, 269, pp. 2865-2868 Davies, P.D., Tuberculosis in the elderly. Epidemiology and optimal management (1996) Drugs Aging, 8, pp. 436-444 Deriemer, K., Rudoy, I., Schecter, G.F., Hopewell, P.C., Daley, C.L., The epidemiology of tuberculosis diagnosed after death in San Francisco, 1986-1995 (1999) Int. J. Tuberc. Lung Dis., 3, pp. 488-493 Franco, J., Blanquer, R., Mortality from tuberculosis in Spain from 1970 to 1993: Changes in epidemiology trends during the acquired immune-deficiency syndrome epidemic (1998) Int. J. Tuberc. Lung Dis., 2, pp. 663-696 Gledovic, Z., Jovanovic, M., Pekmezovic, T., Tuberculosis trends in Central Serbia in the period 1956-1996 (2000) Int. J. Tuberc. Lung Dis., 4, pp. 32-35 Leung, C.C., Yew, W.W., Chan, C.K., Chau, C.H., Tam, C.M., Lato, C.W., Tuberculosis in older people: A retrospective and comparative study from Hong Kong (2002) J. Am. Geratr. Soc., 50, pp. 1219-1226 (2002) Controle Da Tuberculose: Uma Proposta de Integração Ensino-serviço, p. 236. , Ministério da Saúde. Fundação Nacional de Saúde. 5a ed. Rio de Janeiro Oliveira, H.B., Moreira Filho, D.C., Abandono de tratamento e recidiva da tuberculose: Aspectos de episódios prévios, Campinas, SP, Brasil, 1993-1994 (2000) Rev. Saúde Pública, 34, pp. 437-443 Pablos-Méndez, A., Sterling, T.R., Frieden, T.R., The relationship between delayed or incomplete treatment and all-cause mortality in patients with tuberculosis (1996) JAMA, 276, pp. 1223-1228 Rajagopalan, S., Tuberculosis and aging: A global health problem (2001) Clin. Infect. Dis., 33, pp. 1034-1039 Ruffino-Netto, A., Tuberculose: A calamidade negligenciada (2002) Rev. Soc. Bras. Med. Trop., 35, pp. 51-58 Sacks, L.V., Pendle, S., Factors related to in-hospital deaths in patients with tuberculosis (1998) Arch. Intern. Med., 158, pp. 1916-1922 Tollman, S.M., Kahn, K., Garenne, M., Gear, J.S.S., Reversal in mortality trends: Evidence from the agincourt field site, South Africa, 1992-1995 (1999) AIDS, 13, pp. 1091-1097 Zafran, N., Heldal, E., Pavlovic, S., Vuckovic, D., Boe, J., Why do our patients die of active tuberculosis in the era of effective therapy? (1994) Tuberc. Lung Dis., 75, pp. 329-333 Zellweger, J.P., Coulon, P., Outcome of patients treated for tuberculosis in Vaud County, Switzerland (1998) Int. J. Tuberc. Lung Dis., 2, pp. 372-377