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Frequent p53 mutations and occasional loss of chromosome 4 in invasive bladder carcinoma induced by N-butyl-N-(4-hydroxybutil)nitrosamine in B6D2F1 mice
(1998-03-16)
B6D2F1 mice (45/group) were treated with N-butyl-N-(4- hydroxybutyl)nitrosamine (BBN) or uracil as follows: Group 1 received 0.05% BBN in drinking water for the entire experiment, Group 2 received 5 mg of BBN by gastric ...
Frequent p53 mutations and occasional loss of chromosome 4 in invasive bladder carcinoma induced by N-butyl-N-(4-hydroxybutil)nitrosamine in B6D2F1 mice
(1998-03-16)
B6D2F1 mice (45/group) were treated with N-butyl-N-(4- hydroxybutyl)nitrosamine (BBN) or uracil as follows: Group 1 received 0.05% BBN in drinking water for the entire experiment, Group 2 received 5 mg of BBN by gastric ...
Detection of hypermethylation in tumor suppressor genes apaf1, assp1, p73 and fhit in childhood acute lymphoblastic leukemia
(SOCIEDAD CHILENA DE ANATOMIA, 2013)
Can the ATM and TP53 levels influence the low metastasis potential of canine TVT?
(Univ Austral Chile, Fac Ciencias Veterinarias, 2016-01-01)
The study of metastatic progression mechanisms of TVT is necessary. Several prognostic markers have been studied, including ATM genic and protein expression. When present in low expression, this gene is associated to ...
RUNX family: Oncogenes or tumor suppressors
(Facultad de Medicina y Ciencia, 2019)
Runt-related transcription factor (RUNX) proteins belong to a transcription factors family known as master regulators of important embryonic developmental programs. In the last decade, the whole family has been implicated ...