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Occurrence and expression of p53 suppressor gene and c-Myc oncogene in dog eyelid tumors
(2010-03-01)
Purpose: To detect the occurrence and expression of the suppressor gene p53 and of the oncogene c-Myc in eyelid tumors of dogs using the PCR, RT-PCR, PCR-ELISA and RT-PCR-ELISA techniques. These genes have not been described ...
Occurrence and expression of p53 suppressor gene and c-Myc oncogene in dog eyelid tumors
(2010-03-01)
Purpose: To detect the occurrence and expression of the suppressor gene p53 and of the oncogene c-Myc in eyelid tumors of dogs using the PCR, RT-PCR, PCR-ELISA and RT-PCR-ELISA techniques. These genes have not been described ...
High levels of circulating folate concentrations are associated with DNA methylation of tumor suppressor and repair genes p16, MLH1, and MGMT in elderly Chileans
(BIOMED Central Ltd., 2017)
Background: Changes in DNA methylation, one of the most studied epigenetic mechanisms, are considered an initial marker for early cancer detection. We evaluated how availability of dietary factors (folates and vitamin B12) ...
Distinct regions of loss of heterozygosity on 22q at different sites of head and neck squamous cell carcinomas
(2002-04-10)
Background: Frequent loss of heterozygosity (LOH) has been reported in many types of cancer, including head and neck carcinomas. Somatic deletions involving specific chromosomal regions are strongly associated with ...
Distinct regions of loss of heterozygosity on 22q at different sites of head and neck squamous cell carcinomas
(2002-04-10)
Background: Frequent loss of heterozygosity (LOH) has been reported in many types of cancer, including head and neck carcinomas. Somatic deletions involving specific chromosomal regions are strongly associated with ...
Kras oncogene analysis of non-melanoma skin tumors in Southeastern Brazil
(1999-09-01)
Skin cancers are the most common human malignant neoplasia and their incidence is growing, chiefly in tropical countries. There is evidence that ultraviolet (UV) radiation present in sunlight is important for genetic damage. ...
Kras oncogene analysis of non-melanoma skin tumors in Southeastern Brazil
(1999-09-01)
Skin cancers are the most common human malignant neoplasia and their incidence is growing, chiefly in tropical countries. There is evidence that ultraviolet (UV) radiation present in sunlight is important for genetic damage. ...
DNA methylation analysis of tumor suppressor genes in monoclonal gammopathy of undetermined significance
(Springer, 2010-02)
Aberrant DNA methylation is considered an important epigenetic mechanism for gene inactivation. Monoclonal gammopathy of undetermined significance (MGUS) is believed to be a precursor of multiple myeloma (MM). We have ...
Caveolae and caveolae-like membrane domains in cellular signaling and disease: Identification of downstream targets for the tumor suppressor protein caveolin-1
(Society of Biology of Chile, 2002)
Caveolae are small, flask-shaped invaginations of the plasma membrane present on a large number of mammalian cells. Recent results obtained with knock-out mice for the gene caveolin-1 demonstrate that expression of caveolin-1 ...