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Identificação da infecção por Schistosoma mansoni e enteroparasitos em uma área não endêmica para a esquistossomose em Alagoas: associação com fatores de risco e análise espacialIdentification of Schistosoma mansoni and enteroparasites in a non-endemic area for schistosomiasis in Alagoas: association with risk factors and spatial analysis
(Pós-Graduação em Biologia ParasitáriaUniversidade Federal de Sergipe, 2021)
Schistosoma mansoni encodes SMT3B and SMT3C molecules responsible for post-translational modification of cellular proteins
(ELSEVIER IRELAND LTD, 2008)
The sumoylation pathway is a post-translational modification of nuclear proteins widespread among several organisms. SMT3C is the main protein involved in this process and it is covalently conjugated to a diverse assortment ...
The involvement of the spleen during chronic phase of Schistosoma mansoni infection in galectin-3(-/-) mice
(F HERNANDEZMURCIA, 2012)
Schistosoma mansoni synthesizes glycoconjugates which interact with galectin-3, eliciting an intense humoral immune response. Moreover, it was demonstrated that galectin-3 regulates B cell differentiation into plasma cells. ...
Human TNF-alpha induces differential protein phosphorylation in Schistosoma mansoni adult male worms
(Springer, 2016)
Schistosoma mansoni and its vertebrate host have a complex and intimate connection in which several molecular stimuli are exchanged and affect both organisms. Human tumor necrosis factor alpha (hTNF-alpha), a pro-inflammatory ...
Schistosoma mansoni infection and nutritional status in schoolchildren: a randomized, double-blind trial in northeastern Brazil
(1998)
Brazilian schoolchildren with mild- to moderate-intensity schistosome infections (< 400 Schistosoma mansoni eggs/g stool) were randomly allocated to a treatment
(oxamniquine) or placebo group in a double-blind fashion. ...
Schistosoma mansoni infection and nutritional status in schoolchildren: a randomized, double-blind trial in northeastern Brazil
(1998)
Brazilian schoolchildren with mild- to moderate- intensity schistosome infections (< 400 Schistosoma mansoni eggs/g stool) were randomly allocated to a treatment
(oxamniquine) or placebo group in a double-blind fashion. ...
Estudo do perfil de células dendríticas de pacientes com leishmaniose cutânea frente ao antígeno do Schistosoma mansoni Sm29
(2013-07-15)
A resposta imune do tipo Th1 na leishmaniose cutânea (LC) ao tempo em que é responsável pelo controle da infecção, está associada com a lesão tecidual e patogênese da doença. Por outro lado, estudos tem mostrado que a ...
Perfil de citocinas e quimiocinas no sangue periférico de indivíduos com carga parasitaria baixa na infecção pelo Schistosoma mansoni
(Universidade Federal de Minas GeraisUFMG, 2016-10-21)
Schistosomiasis mansoni is a chronic disease and the prolonged and continuous exposure to Schistosoma mansoni antigens results in a deviation of the immune response. For the diagnosis in low endemicity areas, the Kato-Katz ...
In vitro and in vivo anthelmintic activity of (-)-6,6 '-dinitrohinokinin against schistosomula and juvenile and adult worms of Schistosoma mansoni
(Elsevier B.V., 2015-09-01)
The chemotherapy of schistosomiasis relies on the use of praziquantel. However, concerns over drug resistance have encouraged the search for new drug leads. This paper is the first report on the in vitro and in vivo activity ...
In vitro evaluation of permeation, toxicity and effect of praziquantel-loaded solid lipid nanoparticles against Schistosoma mansoni as a strategy to improve efficacy of the schistosomiasis treatment
(Elsevier B.V., 2014-03-10)
Solid lipid nanoparticles (SLN) are a promising drug delivery system for oral administration of poorlywater soluble drugs because of their capacity to increase the solubility of drug molecules when loaded in their lipid ...