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Estrogen effects on pilocarpine-induced temporal lobe epilepsy in rats
(Elsevier B.V., 2009-02-20)
Objetive: To evaluate the effects of conjugated equine estrogens (CEE) on the pilocarpine-induced epilepsy in rats.Study design: 40 female rats were divided into: GPC (positive control) presented status epilepticus (SE) ...
Inducible nitric oxide synthase inhibition attenuates lung tissue responsiveness and remodeling in a model of chronic pulmonary inflammation in guinea pigs
(Elsevier B.V., 2009-02-28)
We evaluated the influence of iNOS-derived NO on the mechanics, inflammatory, and remodeling process in peripheral lung parenchyma of guinea pigs with chronic pulmonary allergic inflammation. Animals treated or not with ...
Prevalence of allergic diseases and/or allergic sensitisation in children and adolescents with type 1 diabetes mellitus
(Elsevier B.V., 2015-03-01)
Background: the prevalence of atopic diseases in children with type 1 diabetes mellitus (DM1) has been reported as lower. the aim of this study was to evaluate the prevalence of allergic diseases and allergic sensitisation ...
SGLT1 activity in lung alveolar cells of diabetic rats modulates airway surface liquid glucose concentration and bacterial proliferation
(Nature Publishing Group, 2016)
High glucose concentration in the airway surface liquid (ASL) is an important feature of diabetes that predisposes to respiratory infections. We investigated the role of alveolar epithelial SGLT1 activity on ASL glucose ...
Inhibition of hydrogen sulphide formation reduces cisplatin-induced renal damage
(Oxford Univ Press, 2011-02-01)
Background. Cisplatin (CP)-induced renal damage is associated with inflammation. Hydrogen sulphide (H(2)S) is involved in models of inflammation. This study evaluates the effect of DL-propargylglycine (PAG), an inhibitor ...
Histologic analysis of Zafirlukast's effect on capsule formation around silicone implants
(Springer, 2007-10-01)
Background: the most common complication experienced by patients who have undergone mammary implant surgery is capsular contracture. This matter concerns physicians and patients, but to date, there is no effective way to ...
The role of Fas ligand protein in the oxidative stress induced by azoxymethane on crypt colon of rats
(Acta Cirurgica Brasileira, 2010-11-01)
Purpose: To study the protein Fas ligand (FasL) on the expression of apoptosis, using a model of oxidative stress induced by azoxymethane (AOM), in the crypt of colon in rats. Methods: Wistar rats (n=14) were assigned into ...
Characterization of a tissue kallikrein inhibitor isolated from Bauhinia bauhinioides seeds: inhibition of the hydrolysis of kininogen related substrates
(Elsevier B.V., 1999-12-01)
Trypsin inhibitors were purified from a saline extract of Bauhinia bauhinioides seeds by ion-exchange column chromatography on DEAE-Sephadex, gel filtration on Superose 12 column, Mono Q ion-exchange chromatography or, ...
COMPARATIVE-STUDY OF 2 TESTS OF RENAL DILUTING ABILITY IN BARTTERS-SYNDROME
(Assoc Bras Divulg Cientifica, 1994-05-01)
1. Different results concerning distal NaCl reabsorption have been reported for patients with Bartter's syndrome in tests of renal diluting ability. We describe clearance studies performed on 3 patients with Bartter's ...
Efeito da cafeína sobre a consolidação tardia da memória de medo em ratos
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2016-07-19)
Caffeine, an antagonist of adenosine receptors, is one of the most widely consumed psychostimulant substance in the world. There are contradicting reports about the effect of caffeine on learning and memory. While some ...