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On the mechanisms of phenothiazine-induced mitochondrial permeability transition: Thiol oxidation, strict Ca(2+) dependence, and cyt c release
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Phenothiazines (PTZ) are drugs widely used in the treatment of schizophrenia. Trifluoperazine, a piperazinic PTZ derivative, has been described as inhibitor of the mitochondrial permeability transition (MPT). We reported ...
Inhibition by phenothiazine derivatives of the adenylate cyclase of amphibian oocytes
(1983)
The adenylate cyclase activity of membranes of Xenopus laevis oocytes and follicle cells was affected by the presence of 2-chloro-10-(3-aminopropyl)phenothiazine (CAPP) and two other antipsychotic drugs, fluphenazine and ...
Novos corantes derivados de vinil-calcogenil fenotiazinas: síntese e estudo das propriedades fotofísicas e eletroquímicas
(Universidade Federal de Santa MariaBrasilQuímicaUFSMPrograma de Pós-Graduação em QuímicaCentro de Ciências Naturais e Exatas, 2022-10-21)
This work presents the synthesis and studies of photophysical and electrochemical
behaviour of new phenothiazines derivatives containing the vinyl-chalcogenyl group in
different positions of the heterocyclic. This research ...
EFEITO DE SURFACTANTES NA ESTABILIDADE DE COMPOSTOS DE USO TERAPEUTICO
(1990-12-01)
A critical revision of literature as regards to the drug stability in the presence of surfactants were realized. The functional groups envolved in the drug decomposition were used to the development of the discussion. The ...
EFEITO DE SURFACTANTES NA ESTABILIDADE DE COMPOSTOS DE USO TERAPEUTICO
(1990-12-01)
A critical revision of literature as regards to the drug stability in the presence of surfactants were realized. The functional groups envolved in the drug decomposition were used to the development of the discussion. The ...
NEW SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF PHENOTHIAZINE DERIVATIVES
(Associação Brasileira de Divulgação Científica (ABRADIC), 2014)